monomer

(redirected from fibrin monomer)
Also found in: Dictionary, Thesaurus, Encyclopedia.

monomer

 [mon´o-mer]
1. a simple molecule of relatively low molecular weight, which is capable of reacting chemically with other molecules to form a dimer, trimer, or polymer.
2. some basic unit of a molecule, either the molecule itself or some structural or functional subunit of it, e.g., an individual polypeptide in a multi-subunit protein.
fibrin monomer the material resulting from the action of thrombin on fibrinogen, which then polymerizes to form the fibrin clot.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

mon·o·mer

(mon'ō-mĕr),
1. The molecular unit that, by repetition, constitutes a large structure or polymer; for example, ethylene, H2C=CH2, is the monomer of polyethylene, H(CH2)nH.
See also: subunit (1).
2. The protein structural unit of a virion capsid.
3. The protein subunit of a protein composed of several loosely associated such units, usually bound noncovalently.
[mono- + -mer]
Farlex Partner Medical Dictionary © Farlex 2012

monomer

A single unit of a multiunit molecule, which are joined to form dimers, trimers and polymers; hydrolysis of polymers yields monomers.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

monomer

A single unit of a multiunit molecule, which are joined to form dimers, trimers, polymers; hydrolysis of polymers yields monomers. Cf Polymer.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

mon·o·mer

(mon'ō-měr)
1. The molecular unit that, by repetition, constitutes a large structure or polymer.
2. The protein structural unit of a virion capsid.
See: virion
3. The protein subunit of a protein composed of several loosely associated such units, usually noncovalently bound together.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

monomer

One of the chemical groups many of which are repetitively linked together to form a POLYMER.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

monomer

any molecule that can exist alone or with other similar molecules to form a polymer.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

mon·o·mer

(mon'ō-měr)
1. The molecular unit that, by repetition, constitutes a large structure or polymer.
2. The protein structural unit of a virion capsid.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
DD levels (0.56 [micro]g/mL and 0.044 [micro]g/mL) were also higher in the bacterial pneumonia patients (p=0.046);however, other fibrinolytic marker FDPs and fibrin monomers were not significantly different (Table II).
Fibrin monomers and FDPs levels were higher in bacterial pneumonia cases, but the difference was not statistically significant.
Inhibition of fibrin monomer polymerisation by myeloma immunoglobulin.
(7) These anionic sugars cause the fibrinogens to polymerize slowly and abnormally, as the increased negative charge causes repulsion between fibrin monomers. (1), (8) The alteration of the fibrin monomers renders them to be poor substrates for thrombin, inhibiting the formation of a clot.
Bleeding is due to fibrinogen mutations that inhibit fibrinopeptide release or fibrin monomer polymerization.
Therefore, the following battery of assays, PT/FIB/D-dimer/CBC, should be adequate in the evaluation of overt DIC, without the inclusion of a fibrin monomer assay.
A novel monoclonal antibody to fibrin monomer and soluble fibrin for the detection of soluble fibrin in plasma.
The authors thank the coworkers from the Department of Laboratory Medicine for the analysis of fibrin monomer. Renaata Hudaak and Jaanos Vincze were supported by the European Union and the State of Hungary, cofinanced by the European Social Fund in the framework of TAMOP4.2.4.A/2-11/1-2012-0001 "National Excellence Program." The publication is supported by the GINOP-2.3.2-15-2016-00043 project.
Thrombin cleaves fibrinogen to form fibrin monomers and release fibrinopeptides A and B.
Its precise role is not yet known, however, and future work is needed to assess its value in comparison with other fibrin-related degradation markers, such as fibrin degradation products or soluble fibrin monomers.
This means that the [alpha]C regions would unravel and the fibrin monomers could partially unfold ([alpha]-helical to [beta]-sheet transition of the [alpha]-helical coiled coils and some other domains could unfold).
We therefore studied plasma concentrations of TpP and fibrin monomers (FMs) in patients with suspected AMI.