fibrin


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fibrin

 [fi´brin]
an insoluble protein that is essential to clotting of blood, formed from fibrinogen by action of thrombin.

fi·brin

(fī'brin),
An elastic filamentous protein derived from fibrinogen by the action of thrombin, which releases fibrinopeptides A and B from fibrinogen in the coagulation of blood; a component of thrombi, vegetations, and acute inflammatory exudates such as in diphtheria and lobar pneumonia.
[L. fibra, fiber]

fibrin

(fī′brĭn)
n.
An elastic, insoluble, whitish protein produced by the action of thrombin on fibrinogen and forming an interlacing fibrous network in the coagulation of blood.

fi′brin·ous adj.

fi·brin

(fī'brin)
An elastic filamentous protein derived from fibrinogen by the action of thrombin, which releases fibrinopeptides A and B from fibrinogen in coagulation of the blood; a component of thrombi, vegetations, and acute inflammatory exudates such as in diphtheria and lobar pneumonia.
[L. fibra, fiber]

fibrin

An insoluble protein that forms as a fibrous network when the blood protein fibrinogen interacts with THROMBIN. Fibrin is the basis of a blood clot and the end product of a complex cascade of reactions set in motion by injury to a blood vessel.

fibrin

see FIBRINOGEN.

Fibrin

The last step in the coagulation process. Fibrin forms strands that add bulk to a forming blood clot to hold it in place and help "plug" an injured blood vessel wall.
References in periodicals archive ?
[3] Active substances such as serotonin, catecholamines, von Willebrand factor, proaccelerin, osteonectin, and antimicrobial proteins released, all of which stimulate cell migration and proliferation within the fibrin matrix, launching the first stages of healing.
When protein S activity, FDPs, and fibrin monomers were evaluated, there was no significant difference between the patient group and the control group (Table I).
The PRF clot [Figure 4b] that was obtained was mixed with osseograft to form a homogenous graft material, and the fibrin is compressed on the defect site along with bone graft and sutured back [Figure 5].
Effect of Platelet-rich Fibrin on Odontoblastic Differentiation in Human Dental Pulp Cells Exposed to Lipopolysaccharide.
Leukocytes trapped in the fibrin matrix secrete some inflammatory and wound healing cytokines (interleukin (IL)-1 [beta], IL-4, IL-6, and TNF-[alpha]) (48).
Platelet-Rich Fibrin and Soft Tissue Wound Healing: A Systematic Review.
It is also important to note that the different synthetic sealant and fibrin glue products used as dural sealants have varying properties and design assemblies that may make them more or less amenable for percutaneous use.
Leukocyte-platelet-rich fibrin (L-PRF) is a second generation of autologous platelet concentration and a fibrin mesh consisting of leukocytes, growth factors, proteins, and cytokines.
As an additional control, fibrin glue without cells (prepared identically to as described above) was included in the experimental set-up.
Thrombelastography was stopped after time to fibrin formation (R), clot formation time (K), and maximal clot strength (MA) were recorded.
After hemostasis was confirmed, autologous fibrinogen and bovine thrombin solution (200 units/mL, prepared using fine granules for oral administration) were sprayed simultaneously onto the ulcer bed to form a layer of fibrin glue to cover the ESD ulcer.
Some of them improve primary hemostasis, others stimulate fibrin formation or inhibit fibrinolysis.6 Some mechanisms are part of the preparation of a procoagulant substance in combination with a vehicle such as collagen matrix, whereas others use a matrix to provide a template for the endogenous coagulation cascade to achieve hemostasis.