fibrin


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fibrin

 [fi´brin]
an insoluble protein that is essential to clotting of blood, formed from fibrinogen by action of thrombin.

fi·brin

(fī'brin),
An elastic filamentous protein derived from fibrinogen by the action of thrombin, which releases fibrinopeptides A and B from fibrinogen in the coagulation of blood; a component of thrombi, vegetations, and acute inflammatory exudates such as in diphtheria and lobar pneumonia.
[L. fibra, fiber]

fibrin

/fi·brin/ (fi´brin) an insoluble protein that is essential to clotting of blood, formed from fibrinogen by action of thrombin.

fibrin

(fī′brĭn)
n.
An elastic, insoluble, whitish protein produced by the action of thrombin on fibrinogen and forming an interlacing fibrous network in the coagulation of blood.

fi′brin·ous adj.

fibrin

[fī′brin]
Etymology: L, fibra, fiber
a stringy insoluble protein produced by the action of thrombin on fibrinogen in the clotting process. Fibrin is responsible for the semisolid character of a blood clot. Compare fibrinogen. See also blood clotting, coagulation, fibrinolysis, thrombin.

fi·brin

(fī'brin)
An elastic filamentous protein derived from fibrinogen by the action of thrombin, which releases fibrinopeptides A and B from fibrinogen in coagulation of the blood; a component of thrombi, vegetations, and acute inflammatory exudates such as in diphtheria and lobar pneumonia.
[L. fibra, fiber]

fibrin

An insoluble protein that forms as a fibrous network when the blood protein fibrinogen interacts with THROMBIN. Fibrin is the basis of a blood clot and the end product of a complex cascade of reactions set in motion by injury to a blood vessel.

fibrin

see FIBRINOGEN.

Fibrin

The last step in the coagulation process. Fibrin forms strands that add bulk to a forming blood clot to hold it in place and help "plug" an injured blood vessel wall.

fibrin

elastic, filamentous, insoluble protein formed as the endproduct of the clotting cascade; derived from plasma fibrinogen (factor I) by the action of thrombin (derived from factor II)

fibrin (fīˑ·brin),

n white, insoluble protein that makes up a blood clot by forming a network in which red blood cells and platelets are trapped; formed by the action of thrombin on fibrinogen.

fibrin

an insoluble protein that is essential to clotting of blood, formed from fibrinogen by action of thrombin.

fibrin-fibrinogen degradation products (FDPs)
the breakdown products of fibrin and fibrinogen, resulting from activation of the fibrinolytic system, they inhibit fibrin formation and platelet adherence. Elevated levels are found in the blood and urine in association with disseminated intravascular coagulation and detection is a test for that condition.
fibrin-fibrinogen split products
see fibrin-fibrinogen degradation products (above).
fibrin foam
a clot promoting surgical material for application to oozing surfaces. Strips of fine white sponge to be soaked in thrombin solution before application.
fibrin glue
a mixture of bovine thrombin and concentrated fibrinogen. It may be used topically or by injection in management of hemostasis.
fibrin plate method
a method of measuring fibrinolytic activity by incubating a fibrin clot with test serum in a Petri dish.
soluble fibrin monomers
a stage in the clot formation process of producing insoluble fibrin monomers.
fibrin stabilizing factor
see fibrin stabilizing factor.
References in periodicals archive ?
Slow natural polymerization of PRF on contact with glass particles of the test tube results in physiologic thrombin concentration, while in PRF sudden fibrin polymerization.
Therefore, we consulted GI specialist for advanced therapy with fibrin glue.
Measured aliquots of AMB-fibrin microsphere were taken in multiple vials to assess the release of AMB from fibrin microsphere.
It converts fibrinogen to fibrin and activates factor XIII, platelets, and smooth muscle constriction (Biologies 2008;2:593-9).
In this study, 50 heart patients following an anticoagulant therapy were treated with leukocyte- and platelet-rich fibrin clots placed into post-extraction sockets.
The deal will allow Ethicon to enter the Chinese fibrin sealant market and to expand its product offering.
The natural response of the body to this trauma is to initiate the healing cascade instigated by the formation of a fibrin clot.
The structural proteins are among the molecules detected earliest at the edge of the wound, in the post-traumatic period and recent work indicates that fibrin can be detected in a time interval as short as 5 minutes after the wound is inflicted (Kondo, 2007).
Molecular aspects and mechanism of action regarding the use of fibrin sealants in laparoscopic gynecology: a literature review