It is also known for influencing fibril formation for collagens type I and II, accelerating fibrillogenesis
and binding to aggrecan, mediating the organization of cartilage matrix for its load bearing function.
Amyloid beta-protein fibrillogenesis
Structure and biological activity of protofibrillar intermediates.
4c, d), suggesting that the fibrillogenesis
process was taking place (see Discussion).
Teplow, "Structural and kinetic features of amyloid [beta]-protein fibrillogenesis
," Amyloid, vol.
Following implantation, the RPC Pure-Collagen reacts with local tissue and fibrillogenesis
is initiated to convert the collagen solution into a fiber matrix.
2007) COMP acts as a catalyst in collagen fibrillogenesis
Small leucine-rich proteoglycans (SLRPs) are ECM proteoglycans required for collagen fibrillogenesis
Results indicate cadmium binds to type I collagen with a higher affinity than calcium and alters collagen fibrillogenesis
A network of thin collagen fibers oriented predominantly in the longitudinal direction with respect to the implant structures is detected in osteointegration zone osteoid, and large functionally active osteoblasts are localized secreting collagen and proteoglycans of bone matrix, as evidenced by pericellular fibrillogenesis
near their surface (Figure 1, a) .
Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis
, the encoded protein may play a role in the assembly of extracellular matrix.
8] Increased type V collagen production may affect normal collagen fibrillogenesis
and alter the mechanical properties of the tissue, leading to improved endurance performance.
Fernandez-Velasco, "Thermodynamic and kinetic characterization of a germ line human A6 light-chain protein: the relation between unfolding and fibrillogenesis
," Journal of Molecular Biology, vol.