fibril


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Related to fibril: fibrillar, amyloid, fibrillar protein

fibril

 [fi´bril]
a minute fiber or filament. adj., adj fi´brillar, fi´brillary.
collagen f's delicate fibrils of collagen in connective tissue, composed of molecules of tropocollagen in linear array. In Type I collagen, the most common type, the tropocollagen molecules are associated in periodic, staggered arrays that give the appearance of cross-banding, forming unit fibrils; these unit fibrils are aggregated in bundles to form larger fibrils, with longitudinal striations, which may themselves be aggregated into fibers.
muscle fibril myofibril.

fi·bril

(fī'bril),
A minute fiber or component of a fiber.
Synonym(s): fibrilla
[Mod. L. fibrilla]

fibril

/fi·bril/ (fi´bril) a minute fiber or filament.fibril´larfib´rillary
collagen fibrils  delicate fibrils of collagen in connective tissue, composed of molecules of tropocollagen aggregated in linear array.
Enlarge picture
Type I collagen fibril (A); it is composed of unit fibrils, here shown negatively stained (B). The unit fibrils themselves comprise tropocollagen molecules in regular staggered arrays (C, D).
dentinal fibrils  component fibrils of the dentinal matrix.
muscle fibril  myofibril.

fibril

(fī′brəl, fĭb′rəl)
n.
1. A small slender fiber or filament.
2. Anatomy A threadlike fiber or filament, such as a myofibril or neurofibril, that is a constituent of a cell or larger structure.
3. A long strand of proteins that are aggregated together in a beta-sheet structure; an amyloid fibril.

fi′bril·lar (-lər), fi′bril·lar′y (-lĕr′ē) adj.
fi′bril·lose′ (-lōs′) adj.

fibril

[fī′bril]
Etymology: L, fibrilla, small fiber
a small filamentous fiber that often is a component of a cell, as in a mitotic spindle or a myofibril. fibrillary, adj.

fi·bril

(fī'bril)
A minute fiber or component of a fiber.
Synonym(s): fibrilla.

fibril

A fine, slender fibre.

fibril

a small FIBRE.

fibril

minute fibre

fibril

a minute fiber or filament.
References in periodicals archive ?
t] are the average cross-sectional area and average length of all the LLDPE fibrils and n is the number of LLDPE fibrils during recovery.
There was a considerable decrease in their ability to take up fibrils and to pass them on to neighboring neurons.
In contrast to most clay-containing blends, in these MFCs, substantial increase in fibril dimensions occurs as a consequence of the clay effect on the competition between the fibril coalescence and extension.
The structures, called amyloid fibrils, are also implicated in neurodegenerative conditions such as Alzheimer's and Parkinson's, and in prion diseases like Creutzfeldt-Jacob and mad cow disease.
The nucleoid displaying fine DNA fibrils occupied the central zone of the cells.
A closer study of the stroma reveals that long collagen fibrils run across the stroma as shown in Figure 1(b) [24].
An alternative approach to the treatment of Alzheimer's disease relies upon inhibiting aggregation of amyloid fibrils with the goal of reducing levels of soluble amyloid-beta peptide.
It also controls fibril dimensions, providing uniformity, cohesion and stabilization to collagen fibers.
On August 19, 2003, ProteoTech was issued United States Patent 6,607,758 entitled "Methods for Inhibiting and Reducing Amyloid Fibril Formation Associated with Alzheimer's Disease and Other Amyloidoses.
The fibrils are joined by bundles of tie fibrils that pass from one fibril to another.