fibric acids


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Related to fibric acids: niacin

fi·bric ac·ids

(fī'brik as'idz),
Drugs structurally related to clofibrate, used to treat hypercholesterolemia and hypertriglyceridemia.
Synonym(s): fibrates
References in periodicals archive ?
Fibric acid derivatives (gemfibrozil [Lopid[R]], fenofibrate [Tricor[R]], clofibrate [Abitrate[R]]) are used to decrease triglyceride levels.
Gemfibrozil, a fibric acid, is often used to treat hypertriglyceridemia and as an adjunctive agent to statin therapy.
There are several types of drugs available for cholesterol lowering including statins, bile acid sequestrants, nicotinic acid, and fibric acids. Your doctor can help decide which type of drug is best for you.
Other LDL-taming medications to discuss with your doctor include bile acid sequestrants and fibric acids.
Niacin is highly effective for elevated triglyceride or low HDL levels even at low doses (200 to 500 mg twice daily), but niacin generally does not lower LDL values to a significant degree until high doses are used.[10] The fibric acids are primarily effective for treating those patients with high triglyceride levels, while the bile acid sequestrant's effectiveness is primarily limited to LDL reduction.
The fibric acid class of drugs include gemfibrozil (Lopid[R]), fenofibrate (Tricor[R]), and clofibrate (Atromid[R]).