fibric acid

[fi´brik]

any of a group of compounds structurally related to clofibrate used to reduce plasma levels of triglycerides and cholesterol.

fibric acid

/fi·bric ac·id/ (fi´brik) any of a group of compounds structurally related to clofibrate that can reduce plasma levels of triglycerides and cholesterol; used to treat hypertriglyceridemia and hypercholesterolemia.

References in periodicals archive ?

13 It is reasonable to study the effect of pioglitazone on lipid profile of non-diabetics and compare it with that of gemfibrozil, a fibric acid derivative, which shows anti-hyperlipidaemic effect by acting on PPAR-a.

Pioglitazone improves serum lipid profile in diet induced hyperlipidaemic non diabetic rats

The dyslipidemia drugs market report estimates the market size (Revenue USD million - 2013 to 2020) for key market segments based on the drug class (bile acid resins, fibric acid and omega-3 fatty acid derivatives, niacin, statins, and other drugs such as combination drugs and cholesterol absorption inhibitors), and forecasts growth trends (CAGR% - 2016 to 2020).

iHealthcareAnalyst, Inc. Announced Dyslipidemia Drugs Market to Reach USD 9.5 Billion by 2020, Decline Due to Patent Expiration and Limited Drugs Innovation

Statins, as well as fibric acid derivatives and niacin, are important considerations in patients with myopathic symptoms.

Myopathy at statin start may have another cause

Or you could substitute another type of cholesterol-lowering drug (bile acid resins, nicotinic acid, fibric acid derivatives, or cholesterol absorption inhibitors) or just work harder on those lifestyle changes that we know can lower cholesterol: a low-fat diet, weight loss, and exercise.

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Fibric acid derivatives, such as fenofibrate, bezafibrate and gemfibrozil, are preferred in the treatment of dyslipidemias associated with DM and metabolic syndrome than HMG-CoA reductase inhibitors as they are usually more effective for normalizing serum levels of HDL-Cholesterol and TG7.

FREQUENCY OF DYSLIPIDEMIAS IN DIABETIC PATIENTS AT COMBINED MILITARY HOSPITAL MULTAN

Hypertriglyceridemia and hyperuricemia: effects of two fibric acid derivatives (bezafibrate and fenofibrate) in a double-blind, placebo-controlled trial.

The beneficial effects of allopurinol in cardiology practice: decrease in uric acid and vascular oxidative stress/the effects of lowering uric acid levels using allopurinol on markers of metabolic syndrome in end-stage renal disease patients: a pilot study/Allopurinolun kardiyoloji pratigindeki faydali etkileri: urik asitte ve vaskuler oksidatif streste azalma/urik asit seviyelerinin allopurinol ile azaltilmasinin son donem..

There are currently 3 fibric acid derivatives, viz.

A reduction in cardiovascular risk is the main aim of most lipid-modifying therapy

Klickstein, fibric acid derivatives, such as losartan, can lower uric acid, and some patients may have improved symptoms with this drug.

Consider new approaches for treating gout

Patients may be prescribed HMG-CoA reductase inhibitors (statins) and fibric acid derivatives for control of lipid and triglyceride abnormalities.

A 47-year-old man with eruptions on his trunk

The antihyperlipidemic class of drugs can be subdivided into bile acid sequestrants, HMG-CoA reductase inhibitors, fibric acid derivatives, ezetim-ibe, and niacin.

Antihyperlipidemic agents

Fibric acid derivatives (gemfibrozil [Lopid[R]], fenofibrate [Tricor[R]], clofibrate [Abitrate[R]]) are used to decrease triglyceride levels.

Update on risk factors for atherosclerosis: the role of inflammation and apolipoprotein E

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