In addition, exposure of pregnant females to a mixture of PCNs roughly corresponding to that used in the past (technical Halowax 1013 and 1014) was found to induce embryotoxic, fetotoxic
and even teratogenic effects .
(11,71) Similar to other maternal infections (eg, TORCH agents) and fetotoxic
insults, exposure in the latter half of pregnancy, after cortical organization is largely completed, may result in less overt neurologic or other impairments that may be detected only later in life.
Serious concerns about the fetotoxic
and reproductive effects of PBDE exposure highlight the importance of further research in this area.
Chronic exposure to arsenic can lead to various health issues like diabetes mellitus, hypertension and as- thma; cancers of skin, liver, kidney, bladder and pro- state have also been reported.5,6 Limited animal studies have shown arsenic compounds to be fetotoxic
and teratogenic.7 Ingested arsenic can cross the placental barrier resulting in its concentration of cord blood comparable to that in the maternal blood.
BPA, melamine, or fetotoxic
or other known carcinogenic compounds.
Also, it is not recommended for women who are pregnant or trying to become pregnant, due to fetotoxic
and abortifacient effects, based on animal studies.
Minor nonspecific fetotoxic
effects are seen in baby rats treated with 50 and 100 mg/kg and in babies of mice treated with 100 mg/kg .
These are indications that the alkaloids are fetotoxic
. The present study differs fro m that previously reported by Yakubu et al.
The significant reduction in mass of the fetuses in the groups treated may indicate a possible fetotoxic
effect [Lyra et al.
(Aluminium, barium and mercury have potential for lethal and intoxicating effects, aluminium and mercury can cause chronic pathologies over time, mercury is carcinogenic for humans, cobalt can cause mutations, and aluminium is fetotoxic
Each entry describes the following: synonyms, brand names, and street names; pharmacologic classifications; availability and use patterns; available dosage forms and routes of administration; the mechanisms of action related to the drug; current approved indications for medical use; reasons for personal use; basic toxicology (including adverse drug reactions); teratogenic and fetotoxic
potential; affects of maternal use on lactation and breast-fed infants; abuse potential; withdrawal symptoms; and overdosage.