fetoprotein


Also found in: Dictionary, Thesaurus, Wikipedia.

fetoprotein

(fē′tə-prō′tēn, -tē-ĭn)
n.
Any of several antigens normally present in a fetus and occurring abnormally in adults as a result of certain cancers or diseases of the liver.

fetoprotein

[-prō′tēn]
Etymology: L, fetus + Gk, proteios, first rank
an antigen that occurs naturally in fetuses and occasionally in adults as the result of certain diseases. An increased amount of alpha-fetoprotein in the fetus is diagnostic for neural tube defects. The presence of beta-fetoprotein in the blood of adults is associated with leukemia, hepatoma, sarcoma, and other neoplasms.

fe·to·pro·tein

, alpha (α)-fetoprotein (AFP) , gamma (γ)-fetoprotein , beta (β)-fetoprotein (fē'tō-prō'tēn, al'fă, gam'ă, bātă)
Fetal proteins found in small amounts in adults in the following forms: 1) AFP increases in maternal blood during pregnancy; when detected by amniocentesis, is an important indicator of neural tube defects (e.g., spina bifida); used as a tumor marker in adults with hepatocellular carcinoma; 2) beta (β)-fetoprotein, although a fetal liver protein, has been detected in adult patients with liver disease; and 3) gamma (γ)-fetoprotein occurs in association with various neoplasms.
See also: fetoglobulins

fetoprotein

(fe?to-pro'ten)
An antigen present in the human fetus and in certain pathological conditions in adults. The amniotic fluid level can be used to evaluate fetal development. Elevated serum levels are found in adults with certain kinds of liver diseases.
See: alpha-fetoprotein
References in periodicals archive ?
The alpha fetoprotein level was found to be high in this patient, but the other tumor markers were found to be normal.
A fetoprotein is a sensitive marker for malignant germ cell tumors like yolk sac tumor and malignant teratoma.
The main aim of the present study was to know the role of the alpha fetoprotein in diagnosis of the premature rupture of the membranes.
Of cases Abdominal distension 14 Lump/mass abdomen 05 Abdominal distension + icterus 01 Beckwith-Wiedemann syndrome 01 Anemia 01 TABLE No: 4 ALPHA FETOPROTEIN LEVELS IN 11 PATIENTS OF HEPATOBLASTOMA LEVELS (IU/ml)) No.
2 Typical presentation of HCC includes solitary mass in normal or cirrhotic liver with elevated alpha fetoprotein.
Occurrence of fetoprotein in patients with neoplasms and non-neoplastic diseases.
The study findings indicate that colchicine prevents or delays the development of HCC independent of factors such as age, platelet count, alpha fetoprotein levels, and transaminase levels.
Alternatively, a patient can opt for integrated screening, in which NT and PAPP-A are measured at 10-14 weeks, followed by the quad screen (serum alpha fetoprotein, hCG, unconjugated estriol, and inhibin A) at 15-16 weeks, and the results are given all at once as a single risk value; if the results are positive, amniocentesis is then offered to the patient.
Complete blood count, liver function test, total protein, Albumin/Globulin (A/G) ratio, serum Albumin, HBsAg, anti HCV, alpha fetoprotein, ultrasound guided liver biopsy, ultrasound whole abdomen and/or CTscan Abdomen for size and number of tumour were also done.
Assay precision of serum a fetoprotein in antenatal screening for neural tube defects and Down's syndrome.