fetal lung maturity


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fetal lung maturity

Obstetrics A parameter that determines the likelihood a neonate will develop RDS; infants delivered at 40 ± 2 wks have 0% incidence of RDS; at 36 wks 0-2%, at 34 wks 8-34%–depending on birthweight

fetal lung maturity

The ability of the developing lung to oxygenate and ventilate effectively outside the womb. The lungs are the last fetal organ to mature. Surfactant, which allows the alveoli in the lungs to expand and not stick together, is secreted by the fetal lungs after 28 weeks. The readiness of the fetal lung can be assessed with several invasive, e.g., amniocentesis, and noninvasive, e.g., ultrasound, tests, all of which have some shortcomings. Some tests on amniotic fluid include: measurements of surfactant; phosphatidylglycerol; the lecithin/sphingomyelin ratio; and the number of lamellar bodies.

Patient care

Premature infants born with immature lungs have a high likelihood of developing infantile respiratory distress syndrome. Antenatal treatment with glucocorticoids improves most amniotic fluid indices of fetal lung maturity. Infants born with immature lungs are also often treated with continuous positive airway pressure, other forms of mechanical ventilation, and surfactant.

See also: maturity
References in periodicals archive ?
Determination of fetal lung maturity by fluorescence polarization of amniotic fluid.
Prediction of fetal lung maturity by use of the Lumadex-FSI test.
Among those who were delivered at 36-38 weeks following documentation of fetal lung maturity, 42.5% had completed 36 weeks, 40.7% had completed 37 weeks, and only 16.8% had completed 38 weeks.
We hypothesise that AFOD is definite marker for labor as well as fetal lung maturity. The findings of our study shows that the corresponding range of AFOD can be measured indirectly using AFPS avoiding amniocentesis.
Lamellar body counts in amniotic fluid for prediction of fetal lung maturity. Arch Gynecol Obstet.
A score of eight to ten is most reassuring, four to six nonreassuring with delivery if fetal lung maturity is adequate.
Fetal wellbeing was monitored daily and fetal lung maturity was induced at 32 weeks of gestation and 2 days with 12 mg of betamethasone repeated at 24 hours.
IV corticosteroids are used widely to treat MS relapses during pregnancy, as well as in obstetrics to speed fetal lung maturity.
Because preterm birth is an important contributor to perinatal morbidity and mortality, steroids should be administered for fetal lung maturity enhancement whenever preterm labor is diagnosed before 34 weeks' gestation.
Introduction of maternal antenatal glucocorticoid treatment to accelerate fetal lung maturity has allowed us to significantly reduce associated morbidity and mortality.
David Grenache focuses on the crucial topic of fetal lung maturity (FLM).
Amniotic fluid is routinely collected during amniocentesis for fetal chromosome analysis or fetal lung maturity studies.