ferritin


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ferritin

 [fer´ĭ-tin]
the complex of iron and apoferritin, a major form in which iron is stored in the body.

fer·ri·tin

(fer'i-tin),
An iron-protein complex, containing up to 23% iron, formed by the union of ferric ions with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver, and regulates iron storage and transport from the intestinal lumen to plasma.
See also: apoferritin.

ferritin

(fĕr′ĭ-tĭn)
n.
An iron-containing protein complex, found principally in the intestinal mucosa, spleen, and liver, that functions as the primary form of iron storage in the body.

ferritin

Hematology A major iron storage protein present in small amounts in serum; in healthy adults, serum ferritin reflects the body's iron store, and can be used to detect iron deficiency Ref range ♂ 33-236 ng/mL; ♀, < 40 yrs 12-263 ng/mL; > 40 yrs 11-122 ng/mL; ↓ Ferritin Hypochromic anemia, microcytic anemia. iron deficiency anemia↑ Ferritin Iron overload, hemochromatosis, inflammation, malignancy

fer·ri·tin

(fer'i-tin)
An iron protein complex, containing up to 23% iron, formed by the union of ferric iron with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver, and regulates iron storage and transport from the intestinal lumen to plasma.

ferritin

The principal IRON-binding protein of the body. Ferritin acts as an iron store in the liver and other tissues. Each ferritin molecule can hold up to 4500 iron atoms and the amount of iron in ferritin molecules accurately reflects the total iron stores of the body. Ferritin also protects against the toxic effects of excess iron.

ferritin

a conjugated, electron-dense protein concerned in the absorption of iron through the intestinal mucosa. It serves as a storage protein for iron in the liver and spleen.

Ferritin

A protein found in the liver, spleen, and bone marrow that stores iron.
Mentioned in: Iron Tests

fer·ri·tin

(fer'i-tin)
An iron protein complex, containing up to 23% iron, formed by the union of ferric iron with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver.

Patient discussion about ferritin

Q. My Iron/TIBC tests normal, Ferritin,Serum = 22. Range 22-322. What is the problem? Iron Bind. Cap. ug/dL 324 range 250 - 450 UIBC ug/dL 206 range 150 - 375 Iron, Serum ug/dL 118 range 40 - 155 Iron Saturation % 36 range 15 - 55 Biopsy = Prostate Cancer....PCA high = 10.2 PSA now 8.3 PSA Ultra W/Serial Monitor ...Ultrasenitive = 8.26

A. What makes you think something is not normal? Ferritin values may be low in some people, and iron deficiency is usually defined as ferritin 15. Do you have anemia? Currently, it doesn't seem you have any problem with the iron levels.

Take care,

More discussions about ferritin
References in periodicals archive ?
The serum ferritin levels of the participating patients were carefully reviewed and females with a hemoglobin (Hb) level of a$?12 mg/dl and males with a hemoglobin level of a$?13 mg/dl, those who received therapy for anemia in the last two months, those who donated blood in the last four months, pregnant women, patients with liver or coronary heart disease, those with infections, those receiving any type of radiotherapy or chemotherapy, patients with kidney disease and those with a hematological disease which could affect ferritin levels were excluded from the study.
Table-2: Haematological parameters in serum ferritin low, normal and high groups.
Linearity for serum ferritin assayed by dilution series (1/4-1/16) while analytical sensitivity was 0.4ng/ml with 94-97% recovery.
The current study was done to determine serum concentrations of ferritin, T3, T4 and TSH in beta-thalassemic major patients on regular blood transfusion and correlation of thyroid function with relation to serum ferritin level.
[21] Low TSAT was defined as <20%, and low ferritin as <100 ng/mL in all children with CKD.[11,12, 221 Absolute ID was defined as low TSAT and ferritin, functional ID as low TSAT and normal ferritin, ID anaemia (IDA) as having ID with anaemia, iron deplete as low TSAT and/or low ferritin, and iron replete as normal TSAT and ferritin.
Prior to FCM therapy, the mean baseline haemoglobin was 106.2 g/L, ferritin 151.2 ug/L and Tsat 15.4% (Table 2), values which were not significantly different from the baseline readings in the IP group (Table 3 pre-IP versus pre-FCM p=0.72, p=0.13, p= 0.06, respectively).
Name, age on the day of test, sex, hemoglobin levels, ferritin levels, weight in Kilogram, status of weight according to WHO Z-score chart for weight for age, height in centimeters (cm.), and status of height according to WHO Z-score chart for height for age were entered on a data form.
Kuhn, "Intestinal ferritin H is required for an accurate control of iron absorption," Cell Metabolism, vol.
Under normal conditions, levels of serum ferritin show a close correlation with iron stores in liver biopsy samples [34], the "gold standard" for measuring the amount of iron in the body.
The influence of factors like duration and amount of blood transfusions, serum ferritin level, and iron chelation therapy on thyroid function was evaluated.
The comparison of BTM patients with and without hemosiderosis revealed that plasma ferritin levels, iron levels, and transferrin saturation index were significantly higher in BTM patients with hepatic hemosiderosis than those without hepatic hemosiderosis (p = 0.021; p = 0.001; p = 0.010, respectively).