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an appetite suppressant used as the hydrochloride salt; unlike the amphetamines, it seems to depress rather than stimulate the central nervous system.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
fenfluraminePondimin®, Redux® Internal medicine An adrenergic appetite suppressing–anorectic amphetamine congener, which, unlike amphetamine, depresses the CNS; fenfluramine ↑ serotonin levels and imparts a sensation of fullness from a lower intake of food and was prescribed as a short-term adjunct in obesity; it was withdrawn from the market following its association with heart valve abnormalities and other cardiac complications Adverse effects Pulmonary HTN, attributed either to serotonic vasoconstriction or altered depolarization of pulmonary vascular smooth muscle membrane. See Fen/Phen.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
fenfluramineA drug used in the management of obesity. It is thought to work by producing a sense of having eaten enough (satiety) rather than by suppressing appetite. There is evidence that fenfluramine may be associated with heart valve disease and PULMONARY HYPERTENSION and it is now rarely used.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005