Crary notes that he has successfully used medication to improve the heart's pumping power in some fen-phen
patients who have serious valve disease.
She discovered the link to fen-phen
and fought to get the evidence reported to Wyeth and the FDA.
Made up of fenfluramine and phentermine, fen-phen
was widely prescribed in the 1990s as a safe and effective way to lose weight.
thing collapsing will turn out to be a big driver in this segment," he notes.
Now, the researchers have defined a circuit in the brain that explains the ways fenfluramine, a component of Fen-phen
, suppresses appetite.
To illustrate the types of complications that bedevil back-end opt-out rights, Part II describes a massive class action lawsuit filed on behalf of millions of users of the diet drugs known as fen-phen
, which were found to cause heart problems.
He insists that Wyeth has largely pushed its fen-phen
and hormone therapy troubles into boxes that it can measure, wrap up and put aside.
In the 1990s, fen-phen
was widely prescribed, with as many as 18 million prescriptions written in 1996 alone (Pitts, Crosby, Laufenberg, Meidinger, & Monson, 1998).
For example, in the Fen-Phen
product liability trial, the cost of discovery for a pharmaceutical company retrieving records from backup tapes was estimated at almost $2 million.
Despite the eye-popping headlines about billion-dollar fen-phen
verdicts or David v.
In addition, certain medications, particularly diet pills such as Fen-Phen
(a combination of fenfluramine and phentermine that was taken off the market several years ago) may cause this condition.
In 1996 the FDA approved the diet drug Redux--which later had to be withdrawn, along with another weight-loss medication involved in the deadly fen-phen
scandal--after its lead reviewer warned of "severe life-threatening risk.