I consider a four-hour insulin profile the single most important laboratory test for assessing not only the glucose metabolism but also for the early detection and quantification of the insulin-toxic states, such as obesity, fatty change
of the liver, prediabetes, diabetes, prehypertension, hypertension, neuropathy, incipient renal failure, and cardiovascular events.
Rana M A and Jawary A H 2011 (10) demonstrated cisplatin induced hepatotoxicity in rats which was manifested as severe fatty changes, congestion, and dilatation of portal vessels & central veins along with multiple necrotic foci.
of liver of group ii albino rat showing congestion (a & b), Vacuolization and fatty changes (c), Pyknotic nuclei (d) h & e stain x 400.
4] for four weeks induced a moderate fibrosis without formation of septa and macro and micro fatty changes
In spite of pretreatment with Livokin, the liver sections showed zone 3 necrosis and fatty changes and Octogen pretreatment showed zone 3 necrosis and periportal fatty changes more in between centrizonal and periportal areas as well as portal areas of necrosis.
The crude liver weight, which was increased after PCM administration may be due to haemorrhages, hydropic degeneration and fatty changes associated with necrosis.
So useful in detection of calcification, hemorrhage, fatty changes
clear and purulent fluid.
The fatty changes
are irreversible even with successful surgery
During efforts to produce a cirrhosis of the liver in animals with alcohol, as well as during experiments designed simply to ascertain the effects of alcohol on its structure, an accumulation of the fat in the liver cells has been found so commonly as the main alteration that a relation between alcohol and fatty changes
in the liver has long been recognized.
Out of 5 subjects having grade III fatty changes
, all 5 (100%) had increased CIMT.
Ultrasound abdomen revealed hepatomegaly with fatty changes
in liver, normal portal and hepatic veins with normal pattern of blood flow.