The photomicrography section of the liver's 40% cassava flour and 60% wheat flour in first week, stained with H/E (X 600) shows moderate fatty change
(MFC) and granulated cytoplasm (GC).
I consider a four-hour insulin profile the single most important laboratory test for assessing not only the glucose metabolism but also for the early detection and quantification of the insulin-toxic states, such as obesity, fatty change
of the liver, prediabetes, diabetes, prehypertension, hypertension, neuropathy, incipient renal failure, and cardiovascular events.
i Gr ii Gr iii Gr iv Hepatic cord pattern Normal Normal Normal Normal Sinusoidal dilatation _ + ++ +++ Focal fatty change
_ + ++ + Vacuolization of hepatocytes _ ++ ++ ++ Pyknosis of hepatocytes _ ++ ++ ++ Apoptosis _ _ _ _ Site and Effects Remarks Hepatic cord pattern No effect observed Sinusoidal dilatation Marked dilatation in grp iv and in other treated grps Focal fatty change
Vacuolization of hepatocytes Equal vacuolization in hepatocytes in all grps Pyknosis of hepatocytes Equal magnitude of damage in all grps Apoptosis No apoptosis was observed in any grp
In case of organophosphorus and organochlorine poisoning major histopathological changes are centrilobular necrosis and sinusoidal dilatation, in carbamate poisoning sinusoidal dilatation is major histopathological change, fatty changes
is predominant among alcohol poisoning, and combined alcohol and insecticidal poisoning major histopathological changes are fatty change
, combined centrilobular necrosis and fatty change
, combined sinusoidal dilatation.
Moreover, fatty changes
(arrow) were also found in group E.
Histological examination of liver using hematoxylin and eosin and Oil Red O staining showed increased accumulation of inflammatory cells and LDs, with macrovesicular fatty changes
and hepatocyte ballooning in liver of HFFD group of rats.
In sections of C[CL.sub.4] + atorvastatin (5 mg/kg) treated livers there was pronounced fatty changes
in the centers of the hepatic lobules and lymphocellular infiltrations in the periportal fields.
weeks induced macro and micro fatty changes
(steatosis), and moderate fibrosis without formation of septa.
On pathological examination the liver shows fatty changes
in the hepatocytes.
In spite of pretreatment with Livokin, the liver sections showed zone 3 necrosis and fatty changes
and Octogen pretreatment showed zone 3 necrosis and periportal fatty changes
more in between centrizonal and periportal areas as well as portal areas of necrosis.
The liver had mild fatty changes
, activated Kupffer cells, and slight lymphoid infiltration in the portal areas.
"These fatty changes
can be reversed but if they're not spotted can lead to cirrhosis and in some cases liver cancers.