familial hemiplegic migraine


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familial hemiplegic migraine

n.
A rare inherited migraine disorder characterized by a temporary paralysis of one side of the body followed by severely throbbing headaches and nausea; it occasionally can cause coma.
References in periodicals archive ?
Domingos et al., "The prevalence of familial hemiplegic migraine with cerebellar ataxia and spinocerebellar ataxia type 6 in Portugal," Headache, vol.
Tuna et al., "Phenotypes of spinocerebellar ataxia type 6 and familial hemiplegic migraine caused by a unique CACNA1A missense mutation in patients from a large family," Archives of Neurology, vol.
Familial hemiplegic migraine with crossed cerebellar diaschisis and unilateral meningeal enhancement.
(2009) Ca(V)2.1 P/Q-type calcium channel alternative splicing affects the functional impact of familial hemiplegic migraine mutations: implications for calcium channelopathies.
Other diseases affect the central nervous system, such as familial hemiplegic migraine (FHM), episodic ataxia type 2 (EA-2), and spinocerebellar ataxia type 6 (SCA6).
Genetic research, however, has already identified familial hemiplegic migraine, a rare form of complicated migraine, to be caused by a genetic defect on chromosome 19, one of the 26 strands of DNA in human cells.
A genetic deficiency in voltage-gated calcium channels was identified in patients with familial hemiplegic migraine and type II episodic ataxia; these two paroxysmal diseases are characterized by vertigo and migraine as the major symptoms [68].

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