familial cancer

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fa·mil·i·al can·cer

cancer aggregating among blood relatives; rarely the mode of inheritance is clearly mendelian, either dominant, as in retinoblastoma, basal cell nevus syndrome, neurofibromatosis, and intestinal polyposis, or recessive, as in xeroderma pigmentosum.
See also: cancer family.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Boland, "Inversion of exons 17 of the MSH2 gene is a frequent cause of unexplained Lynch syndrome in one local population," Familial Cancer, vol.
Zhang, "Analysis of [p27.sup.Kip1] expression in insulinomas developed in pancreatic [beta]-cell specific Men1 mutant mice," Familial Cancer, vol.
Von Hippel-Lindau (VHL) disease a familial cancer syndrome characterized by benign or malignant tumors and cystic lesions affecting multiple systems.
Roviello, "Familial gastric cancer: update for practice management," Familial Cancer, vol.
Middelton et al., "Diagnosis and management of BHD-associated kidney cancer," Familial Cancer, vol.
Rhabdomyosarcoma in children: epidemiologic study and identification of a familial cancer syndrome.
According to the company, its Cancer Origin Test 'Value of microRNA-based molecular profiling in Cancer of Unknown Primary (CUP) cases for familial cancer risk assessment and genetic counseling', will be presented by study author and medical geneticist, E.
Management of extraocular sebaceous carcinoma is complicated by its association with the familial cancer syndrome, Muir-Torre Syndrome.
Loss of function mutations in this protein have been attributed to Brit-Hogg-Dube syndrome (BHD), an autosomal dominant familial cancer associated with an increased risk of kidney cancer.
An estimated 15% to 20% of colorectal cancers are related to a familial cancer syndrome.
With the seven newly discovered DNA regions, scientists are now able to explain about 25 percent of familial cancer risk.
Concise handbook of familial cancer susceptibility syndromes - second edition.

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