The drugs used for the treatment of herpes zoster are Acyclovir, Valacyclovir and Famcyclovir
, Desiclovir, Penciclovir and Foscarnet.
Oral valacyclovir and famcyclovir
are equivalent to oral acyclovir.
Among other alternatives of antiviral management, foscarnet, brivudine, famcyclovir
or valgancyclovir are present.
Prescribing valacyclovir or famcyclovir
, each of which requires fewer daily doses than acyclovir, may be the best choice to ensure compliance in these cases, she said.
Two were reported significantly more often with famcyclovir
: diarrhea (5% vs.
Two adverse events were reported significantly more often in patients taking famcyclovir
: diarrhea (5% vs.
Recently developed antiviral drugs, such as acyclovir and famcyclovir
, lessen the symptoms and frequency of recurrences for some patients.
Traditional prescription medications to prevent and treat cold sores include Acyclovir (Zovirax), valacyclovir (Valtrex), and famcyclovir
Famcyclovir, a new antiviral agent was approved for marketing by FDA in June 1994 for the management of acute Herpes Zoster.
It selectively gets activated in virus infected cells through phosphorylation to antiviral compound Famcyclovir triphosphate.
The mean number of days taken for full crusting, complete healing of lesions and acute loss of pain in valacyclovir group was 9.73 days, 20.32 days and 21.03 days respectively; in Famcyclovir group was 10.43 days, 20.66 days and 22.15 days and p-values were calculated as seen in [Table 5/Fig.
The time taken for full crusting in both the groups in patients above 60 years of age was 13.75 days in Valacyclovir and 12.8 days in Famcyclovir. Time taken for complete healing was 22.5 days in Valacyclovir and 22.6 days in Famcyclovir, for acute loss of pain was 23.5 days in Valacyclovir and 24.6 days in Famcyclovir group.