falciparum malaria


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fal·cip·a·rum ma·lar·i·a

malaria caused by Plasmodium falciparum and characterized by malarial paroxysms of severe form that typically occur every 48 hours with acute cerebral, renal, or gastrointestinal manifestations in severe cases, chiefly caused by the large number of red blood cells affected and the tendency for such infected red blood cells to become sticky and clump, thus blocking capillaries.
See also: malarial knobs.

fal·cip·a·rum ma·lar·i·a

(fal-sip'ă-rŭm mă-lar'ē-ă)
Disease caused by Plasmodium falciparum and characterized by intense malarial paroxysms that after synchronization occur every 48 hours with acute cerebral, renal, or gastrointestinal manifestations in severe cases, chiefly caused by the large number of red blood cells affected and the tendency for infected red blood cells to become sticky and then clump, thus blocking capillaries.
Synonym(s): malignant tertian malaria.

falciparum malaria

The most dangerous form of MALARIA caused by the parasite Plasmodium falciparum . There is severe breakdown of red blood cells, sometimes with so much release of HAEMOGLOBIN that it appears in the urine (BLACKWATER FEVER). Falciparum malaria also features blockage of small blood vessels by parasite and toxic effects on the linings. The consequent damage to organs, including the brain, is a major danger.
References in periodicals archive ?
Artesunate for the treatment of severe falciparum malaria. N Engl J Med 2008;358(17):1829.
Relative lymphocytosis was seen in total 75.4% of falciparum malaria (40 cases) and 80% of vivax malaria (12 cases).
Population dynamics of untreated Plasmodium falciparum malaria within the adult human host during the expansion phase of the infection.
Atypical presentations of Falciparum malaria. J Assoc Phys India.
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria. Nature.
Fairhurst et al., "Spread of artemisinin resistance in Plasmodium falciparum malaria," The New England Journal of Medicine, vol.
In 1985-1986, MSP cured over 98% of 5,192 patients with falciparum malaria on the Thai-Myanmar border.
The concentration of mefloquine found in adult patients was similar to that reported in previous studies which investigated healthy Caucasian volunteers and patients with uncomplicated falciparum malaria from Thailand and Peru.
Changes in white blood cells and platelets in children with falciparum malaria: Relationship to disease outcome.
Data source: An open-label, randomized clinical trial in which resistance to artemisinins was tracked across Southeast Asia, India, and Africa in 1,241 patients with acute uncomplicated falciparum malaria.
vivax in children across Sindh were observed.14 A review of falciparum malaria has also been published.15 High incidence of P.