factor X deficiency

Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia.

factor X deficiency

An autosomal-recessive condition caused by a mutation on chromosome 13q34, resulting in decreased factor X production.

Clinical findings

• Infancy—Severe umbilical cord stump bleeding, prolonged bleeding following circumcision
• Childhood—Recurring nose-bleeds, easy bruising, hemarthroses.
• Ob/Gyn complaints—Menorrhagia, spontaneous first-trimester abortion, postpartum bleeding.
Other complications—Haematuria; excessive bleeding due to surgery or trauma; pseudotumours; intracranial bleeding; bleeding in soft tissues, muscles, and gut.

References in periodicals archive ?

M2 EQUITYBITES-May 24, 2018-Bio Products' first and only US FDA-approved Coagadex for hereditary factor X deficiency granted priority review

Bio Products' first and only US FDA-approved Coagadex for hereditary factor X deficiency granted priority review

Liver disease: Although factor X may decrease with significant liver disease, this would not explain an isolated factor X deficiency. With liver disease (or vitamin K deficiency/antagonism), factor VII is usually the first factor to decrease as it has the shortest half life of all procoagulant factors produced in the liver.

Factor X deficiency

Medication management company Diplomat Pharmacy (NYSE:DPLO) and its affiliate companies Thursday announced plans to begin distribution of Coagadex (coagulation factor X, human) for the treatment of the Hereditary Factor X Deficiency with effect from December 2015.

Diplomat to distribute COAGADEX for treating Hereditary Factor X Deficiency under an agreement with Bio Products Laboratory

M2 PHARMA-October 23, 2015-Diplomat to distribute COAGADEX for treating Hereditary Factor X Deficiency under an agreement with Bio Products Laboratory

Diplomat to distribute COAGADEX for treating Hereditary Factor X Deficiency under an agreement with Bio Products Laboratory

Full browser ?

CITE

Site: Follow: Share:

Open / Close