factor VII deficiency


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Related to factor VII deficiency: Factor xi deficiency, Factor VIII deficiency

factor VII deficiency

Molecular medicine A coagulopathy which may be either inherited–AR due to a mutation resulting in a defect in factor VII, or acquired either due to a vitamin K deficiency, appearing in the neonatal period or due to an excess of factor VII in some Pts with thromboembolism Clinical Epistaxis, mucosal hemorrhage. See Factor X.
References in periodicals archive ?
Thrombosis in inherited factor VII deficiency. J Thromb Haemost 2003; 1: 2153-8.
Acquired factor VII deficiency not due to vitamin K deficiency or liver disease is rare but has been reported in patients with sepsis, malignancy, post-operative state and in patients undergoing bone marrow transplantation.
Among the 273 coagulation factor deficiency patients, inherited coagulation factor deficiencies including factor VIII deficiency in 121 (44.3%), factor IX deficiency in 32 (11.7%), factor V deficiency in 18 (6.6%), factor XIII deficiency in 15 (5.5%), factor VII deficiency 12 (4.4%), factor X deficiency 9 (3.3%), factor I deficiency in 8 (2.9%), factor II deficiency in 3 (1.1%).
(11.) Lapecorella M, Mariani G; International Registry on Congenital Factor VII Deficiency: Factor Vii deficiency: Defining the clinical picture and optimizing therapeutic options.
Potential predictors of bleeding risk in inherited factor VII deficiency: clinical, biological and molecular criteria.
Recombinant factor VIIa for treatment of a child with severe factor VII deficiency and coarctation of the aorta.
Another patient, a 28-year-old man, had been diagnosed with a factor VII deficiency (activity: 20%) during childhood, but he did not undergo detailed analysis or experience any post-tonsillectomy bleeding.
Factor VII deficiency: immunological characterization of genetic variants and detection of carriers.