factor V Leiden mutation A

factor V Leiden mutation A

Hematology A mutation of factor V gene resulting in resistance to activated C protein; a common inherited cause of thrombosis
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In hereditary forms, the most frequent anomaly is factor V Leiden mutation as shown by a study in an Egyptian population (Elasal et al 2014).
Massive pulmonary embolism and thrombophilia
Conclusion: FVL mutation and Protein C and S are the leading causes of thrombophilia with strong association of Factor V Leiden mutation as risk for developing DVT.
High prevalence of protein C protein S antithrombin deficiency and Factor V Leiden mutation as a cause of hereditary thrombophilia in patients of venous thromboembolism and cerebrovascular accident
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