facilitated diffusion


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fa·cil·i·tat·ed trans·port

the protein-mediated transport of a compound across a biomembrane that is not ion-driven; a saturable transport system.
Synonym(s): passive transport

facilitated diffusion

Carrier-mediated transport of a non-charged molecule down its chemical gradient via a specific membrane-integrated protein.

facilitated diffusion

The movement of a substance (such as glucose) through a cell membrane along a concentration gradient with the help of membrane proteins acting as carrier molecules.
See also: diffusion
References in periodicals archive ?
(1984) pointed out that under conditions of submaximal rates of aerobic energy turnover, the role of phosphagens can be viewed as a form of facilitated diffusion in which the phosphagen and its corresponding guanidine base, in effect, substitute for ATP and ADP, respectively.
In addition to the facilitated diffusion approach, high-energy phosphate transport in vivo has also been investigated extensively using reaction-diffusion models (Raft and Blum, 1968; Nevo and Rikenspoel, 1970; Lin, 1972; Tombes et al., 1985; Hubley et al., 1997); these models require the use of in vivo D values that are typically somewhat lower than corresponding in vitro D values (Moonen et al., 1990; Hubley et al., 1995).
Furthermore, the facilitated diffusion model is applicable only to situations in which aerobic energy turnover is near or below maximal and the global cellular high-energy phosphate concentrations do not change appreciably (or at least reach a new steady state).

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