extrapyramidal side effects


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extrapyramidal side effects

side effects that mimic extrapyramidal disease and are caused by drugs that block dopamine receptor sites in the extrapyramidal system tract. See also parkinsonism.
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Instead, researchers often focus on exploring potential benefits because long-term effects of antipsychotics, including sedation, weight gain, metabolic syndrome, and extrapyramidal side effects, are well documented.
5) Ondansetron has been reported to cause extrapyramidal side effects in a considerable number of cases.
Her relatives told that, during her previous surgery, symptoms resembling extrapyramidal side effects had been observed following administration of metoclopramide.
In addition to the previously mentioned sedation and orthostasis, typical antipsychotics are much more likely to cause elevated prolactin levels and extrapyramidal side effects.
The authors further stressed that when prescribing antipsychotics, it is imperative to regularly monitor both their efficacy and tolerability in patients through body weight, fasting lipids and glucose, extrapyramidal side effects, sedation, and sexual/reproductive adverse effects, and to manage abnormalities appropriately.
His compliance with the treatment schedule was high, but there were extrapyramidal side effects with partial remission.
Ziprasidone###80-200###Sedation, autonomic side effects, extrapyramidal side effects
Arguing that as long as dopamine antagonism is the target antipsychosis action, extrapyramidal side effects (EPS) may be to some extent inevitable depending on the parameters set, Owens presents this more than 80 percent rewritten second edition.
Extrapyramidal side effects include early onset dyskinesias, such as dystonias (twisting of the neck or facial spasms); akathisia (inner restlessness with inability to sit still); and Parkinsonian symptoms (bradykinesia, pill-rolling tremor or shuffling gait); and late onset dyskinesias, such as tardive dyskinesia (irregular jerking movements of the face and extremities) and dystonia.
Antipsychotic agents are usually first-line pharmacological therapies for delirium, but these agents are sometimes ineffective in this setting, and are associated with adverse events such as prolongation of the QT interval, and with extrapyramidal side effects such as akathisia, tremors, and, less frequently, the neuroleptic malignant syndrome, Dr.
Olanzapine, risperidone, and quetiapine are associated with a higher risk of weight gain, and aripiprazole and ziprasidone have been linked to a higher risk of extrapyramidal side effects.
Late extrapyramidal side effects of antipsychotic therapy are not rare, and their treatment by replacing antipsychotics with anticholinergics, anxiolytics, levodopa, botulinum toxin and physical therapy is often unsuccessful [39].

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