Besides improving cross-species
extrapolation, the EGP will enable "the design of epidemiological approaches that allow us to identify more subtle effects and therefore identify either susceptibilities or adverse impacts much earlier and much more quickly than we might have," Farland says.
distinguish between adaptive and adverse responses), and d) demonstrate how "omics" can reduce uncertainties associated with animal-to-human
extrapolation.
In an
extrapolation of our results,' note the psychiatrists, "even a conservative estimate would place the annual prevalence of [NMS] in the United States in the thousands of cases, a significant number of which may have fatal consequences.
In justifying its regulations, HHS said they were a natural
extrapolation of the Rehabilitation Act of 1973, which prohibits discrimination against the handicapped by institutions or programs receiving federal funds.
A powerful and popular numerical procedure, Richardson
extrapolation can improve the performance of computer programs that handle large time-dependent scientific and engineering problems, say Zlatev and colleagues, and scientists and engineers often use it in their treatment of advanced large-scale mathematical models of various phenomena.
The strategy document encourages medicine developers to make better use of:
extrapolation of available clinical data, including through appropriate modelling and simulation techniques, to predict how a medicine may work in children and adolescents on the basis of studies conducted in adults or other paediatric populations; the possibility to test the safety and efficacy of medicines developed by different companies in one single trial, so-called multi-arm, multi-company clinical trials.
Numerical Methods Coupled with Richardson
Extrapolation for Computation of Transient Power Systems
Across the Boundaries:
Extrapolation in Biology and Social Science.
2011) appears consistent with the intent of the POD to characterize "the beginning of
extrapolation to lower doses" [U.
The polynomial interpolation and
extrapolation methods [3-12,19], the rational polynomial approaches [13-18,20], and other techniques [21-27] have been proposed for fast generating the MoM matrices, the current distributions, and the radar-cross-section (RCS) results over a frequency band.
