The demonstration that many PCBs block SXR in humans rather than activate it--as previously thought, based on animal models--challenges the assumption that animal models
extrapolate to humans.
The heart of the forecasting problem is that most forecasters merely
extrapolate forward from experience of the recent past, where, in the real world, life itself tends to run in cycles.
Cole and Arundel reasoned that if they could determine an ancient temperature within the canyon, they could
extrapolate to the temperature at the rim and in the surrounding area.
Thus, it is critical to improve animal models of thyroid disruption as well as advance our ability to
extrapolate animal data to human risk.
"There's a lot of useful work that went into that effort that we can use and
extrapolate from," he said.
Then, they
extrapolate the data to a larger simulation comprising hundreds of thousands of atoms and then to millions of atoms or more.
To monitor urban air quality, environmental agencies typically measure pollutant concentrations in samples collected at centralized outdoor locations and
extrapolate individuals' average exposures from those measurements.
In the design of the Sacklet Galleries at the Royal Academy (AR December 1991), and more recently the Duisberg Masterplan, the practice has demonstrated an ability to grasp the essence of what exists and
extrapolate from it.
Steidel cautions that because today's telescopes can only detect the brightest distant galaxies, "it is hard to
extrapolate what [the new findings] mean about galaxy formation in general."
The researchers
extrapolate that across Indonesia, the 1997-1998 fires released a total of 0.81 to 2.57 billion tons of carbon into the air.
