The pathogenesis of
extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) appears to be associated with environmental factors, such as bacterial infections, that drive inflammatory response that may evoke acquisition of oncogenic mutations.
Zhang, "Primary
extranodal marginal zone lymphoma of the endometrium: report of four cases and review of literature," International Journal of Clinical and Experimental Pathology, vol.
Primary cutaneous marginal zone B-cell lymphoma is considered as part of
extranodal marginal zone lymphoma of MALT type [3].
Mucosaassociated lymphoid tissue (MALT) lymphoma arises from B cells and is a type of
extranodal marginal zone lymphoma [2].
MALT lymphoma, also called
extranodal marginal zone lymphoma of the MALT, arises in a number of epithelial tissues; this most area are the gastric, ocular, bowel, pulmonary and salivary glands.[sup.4]
30%) is
extranodal marginal zone lymphoma. The
extranodal marginal zone lymphomas of MALT type are generally associated with Hashimoto thyroiditis.
Findings on pathologic examination were consistent with
extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma).
(3) Reported primary lymphomas include chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), follicular lymphoma, and
extranodal marginal zone lymphoma. (4-10) Histiocytic sarcoma has also been reported as a second malignancy after chemotherapy for germ cell tumors of the gonads or mediastinum.
Non-Hodgkin lymphoma of the breast is exceedingly rare; the majority diagnosed are of B-cell origin including diffuse large B-cell lymphoma,
extranodal marginal zone lymphoma, follicular lymphoma, primary effusion lymphoma, and lymphoplasmacytic lymphoma [5-7].
A variety of small B-cell lymphomas can involve the GI tract, the most common being
extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma).
(10,17,21) Primary cutaneous marginal zone lymphoma, a variant of
extranodal marginal zone lymphoma that is limited to the skin at diagnosis, is a low-grade B-cell lymphoma with a favorable prognosis (5-year survival of 90%-100%).
Pulmonary
extranodal marginal zone lymphoma with massive crystal storing histiocytosis.
