involvement in multiple myeloma," Haematologica, vol.
Myeloid sarcoma is a rare extramedullary
tumor composed of malignant myeloid cells that occur in the presence of myeloid leukemia.
Multiple myeloma is a malignancy that is usually limited to bone marrow involvement, but extramedullary
involvement may occur at a rate of 3%.
Moreover, hematological abnormalities such as thrombocytopenia, anemia, susceptibility to infections, and extramedullary
hematopoiesis can result because of the decrease in hematopoietic cells.
Type III: Juvenile-type intra + extramedullary
plasmacytoma is a rare cause of an intra-abdominal mass.
(1) There are two types of solitary plasmacytomas: extramedullary
plasmacytomas, which occur in the soft tissue and solitary plasmacytoma of bone (SPB).
Tumor related factors include location (dorsal, ventral, or lateral), extension (intraspinal, foraminal, and/or extraforaminal components, contiguous vertebral segments involved), affected neural compartments (intradural extramedullary
, intraextradural, purely extradural, intramedullary, or intraosseous), size, and "modified Sridhar classification of benign NSTs" (nongiant, giant).
The CT features were typical of extramedullary
Complete haematological remission (CHR) was defined as absolute neutrophil count (ANC) of 1.0 x 109/L, Platelet count of [greater than or equal to]100,000/ul, bone marrow aspirate with <05% blasts and no extramedullary
disease after 1 month of induction therapy.
Aside from these two cases, common characteristics of patients-irrespective of their clinical presentation-are: a predominant myelomonocytic/monocytic lineage involvement; poor prognosis (median survival 7 months) and a high incidence of extramedullary
involvement (myeloid sarcoma), mainly as skin lesions.
Involvement of extramedullary
sites especially reproductive organs can be extremely challenging due to their masquerading, atypical clinical presentations and impact to fertility (7,8,9).