extrachromosomal DNA


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ex·tra·chro·mo·som·al DNA

DNA that occurs naturally outside of the nucleus (for example, mitochondrial DNA).

extrachromosomal DNA

DNA which is independent of the host's chromosomal DNA. See for example PLASMID.
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References in periodicals archive ?
The assay most commonly used for SCID-NBS is real-time PCR to measure T-cell receptor excision circles (TREC), extrachromosomal DNA byproducts of somatic recombination in T cells (10).
Newborn blood spot screening test using multiplexed real-time PCR to simultaneously screen for spinal muscular atrophy and severe combined immunodeficiency
chlorotica without a gene transfer event incorporated into the germ line, including the possibility of extrachromosomal DNA fragments taken up during feeding and missed in the adult sequencing efforts (Bhattacharya et al.
FISH labeling reveals a horizontally transferred algal (Vaucheria litorea) Nuclear Gene on a Sea Slug (Elysia chlorotica) Chromosome
So we're delivering extrachromosomal DNA that has all the 'start' and 'stop' signatures and other information the cell needs to make the appropriate protein, in this case, the missing enzyme.
Pioneering gene therapy for children
Extrachromosomal DNA isolation and agarose electrophoresis.
In those systems, extrachromosomal DNA genes may have contributed to the ability of the isolates to degrade oil.
Hydrocarbon degrading bacteria at Oil Springs, Texas
For this analysis, we used an approach that had previously been used successfully for the characterization of rare linear extrachromosomal DNA species (21).
Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms
In human cells, mitochondria are the only organelles that contain extrachromosomal DNA.
Quantification of mitochondrial DNA deletion, depletion, and overreplication: application to diagnosis
Transgenic animals generated by microinjection of DNA solution into the germline syncytium usually contains multicopy repetitive extrachromosomal DNAs that are silenced in the germline but expressed in the somatic cells.
Comprehensive functional genomics using Caenorhabditis elegans as a model organism
Homologies between the contiguous and fragmented rRNAs of the two Plasmodium falciparum extrachromosomal DNAs are limited to core sequences.
Molecular analysis of Plasmodium ovale variants
A bacterial genome if flux; the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi.
Comparative Genomics and Understanding of Microbial Biology

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