The aim of this study was to investigate adjuvant radiotherapy for thymoma with MG after extended thymectomy. Methods: A total of 181 patients with both MG and thymoma were recruited between 2003 and 2014 at Tongren Hospital, China.
Our former studies revealed that some MG patients with thymoma experienced exacerbation of MG over 1 month after surgery and postoperative myasthenic crisis is the main cause of death for thymoma patients with MG. According to our experience, it seemed that adjuvant mediastinal radiation therapy within 1 month after extended thymectomy might not only decrease the incidence of postoperative myasthenic crisis but also might have impact on long-term outcome.
Between 2003 and 2014, 181 patients with MG and thymoma underwent extended thymectomy by video-assisted thoracoscopic surgery ( n = 172) or the transsternal approach ( n = 9). Briefly, thymoma was diagnosed by experienced neurologists according to both contrast-enhanced computed tomography and symptoms.
Video-assisted thoracoscopic extended thymectomy (VATS-ET) is well established in the treatment of MG if medical treatment is failed.
Up to now, intubated general anesthesia (GA) and one-lung ventilation using double-lumen tube are still a standard anesthetic method for cases of myasthenia gravis (MG) undergoing video-assisted thoracoscopic extended thymectomy (VATS-ET).
reported three MG patients receiving transsternal, extended thymectomy under high TEA with intermittent bolus midazolam sedation.