analyzed effects of alpha-blockers (tamsulosin and doxazosin) on stone
expulsion rate, stone expulsion time, and treatment-emergent adverse events with four RCTs and one cohort study.
Many studies have shown the efficacy of MET in distal ureteric stones with primary aim of improving stone
expulsion rates. Ahmad et al23 has shown an effective stone
expulsion rate of more than 85% for tamsulosin group while only 55% rate for patients without tamsulosin treatment.
Studies have reported
expulsion rate of 3.8% to 12%.13-22 Our study showed
expulsion rate of 6%; 6.7% with spontaneous vaginal delivery (SVD) versus 4.3% with caesarean section although not statistically significant.
The study group showed higher stone
expulsion rate (100%) and time to expulsion (M = 10.34 days) than control.
While the
expulsion rate was higher than seen generally, it is still an effective method for most obese women.
Keep in mind that there is a somewhat higher
expulsion rate for IUDs placed in the immediate postpartum period.
Expulsion rate of 4.7% is quite low as in another study the
expulsion rate was 9% postplacental and 37% if placed postpartum17 (fig-2).
(7) in Turkey in 2011 noted an
expulsion rate of 17.6% at 12 months with the TCu380A IUD inserted immediately following cesarean section delivery.
(24) However, even if IUD insertion is performed immediately postpartum, there is a higher
expulsion rate than when the IUD is inserted [greater than or equal to]4 weeks postpartum.
It increases the
expulsion rate and decreases the expulsion time, thereby reducing the cost and lost working days.
However, a study demonstrated that
expulsion rate with single dose of 400 mcg oral misoprostol was about 13 % [25], while, another study demonstrated that repeated doses of 400 mcg misoprostol can lead to increased
expulsion rate up to 70% [26, 27].
indicated that tamsulosin increases stone
expulsion rate [25].
