experimental allergic encephalomyelitis

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ex·per·i·men·tal al·ler·gic en·ceph·a·lo·my·e·li·tis (EAE),

a demyelinating allergic encephalomyelitis produced by the injection of brain tissue, usually with an adjuvant.
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References in periodicals archive ?
Brosnan, "A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4 deficient C57BL/6 mice and BALB/c mice," Journal of Immunology, vol.
Attenuation of experimental allergic encephalomyelitis in complement component 6-deficient rats is associated with reduced complement C9 deposition, P-selectin expression, and cellular infiltrate in spinal cords.
Bolton, "Inhibition of blood-brain barrier disruption in experimental allergic encephalomyelitis by short-term.
Staphylococcal enterotoxin B and tumor necrosis factor-a-induced relapses of experimental allergic encephalomyelitis: protection by transforming growth factor- and interleukin-10.
Owens, "Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice," Journal of Immunology, vol.
Levi-Schaffer, "Mast cells in experimental allergic encephalomyelitis: characterization, distribution in the CNS and in vitro activation by myelin basic protein and neuropeptides," Journal of the Neurological Sciences, vol.
Such data often come from laboratory studies, often with laboratory mice or rats that have EAE (experimental allergic encephalomyelitis), which is very similar to MS.
Mice with experimental allergic encephalomyelitis (EAE) show many of the same symptoms as humans with MS, and the mouse disease progresses similarly.
Hooper, "Loss of blood-brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models," Proceedings of the National Academy of Sciences of the United States of America, vol.

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