"The relation of the sympathetic nervous system and generalized lymphoid hyperplasia to the pathogenesis of exophthalmic goiter and chronic lymphatic leukemia." Amer J Med Sci, 1932; 183:841-849.
"The effect of Lugol's solution on chronic lymphatic leukemia and its bearing upon the pathogenesis of exophthalmic goiter." Am J Med Sci, 1932; 183:515-529.
"The effect of Lugol's solution on the elevated basal metabolism in conditions other than exophthalmic goiter." J Clin Invest, 1931; 10:172.
He was against the use of iodine/iodide in exophthalmic goiter and all forms of hyperthyroidism.
Cowell and Mellanby in their 1925 publication (60) give a glimpse of Kocher's influence over the thyroidologists of that time, bordering on intimidation, "Kocher taught that the administration of potassium iodide must never be carried out in exophthalmic goiter, and on the whole, this advice has been taken.
In 1927, DeCourcy (61) stated, "That the administration of iodine prior to operation for exophthalmic goiter controls the symptoms, lowers the basal metabolic rate and lessens the hazards of operation, is no longer questioned.
From January 1 to September 1, 1924, from 600 to 700 new cases of exophthalmic goiter were observed in the Clinic.
Plummer as a method of preparation for operation in exophthalmic goiter marks a step of forward progress in the surgical management of this disease.
Thompson, et al (57) published the results obtained in 24 patients with exophthalmic goiter treated with Lugol solution alone without surgery, using a daily dose of one drop.
Starr, et al (65) from the Massachusetts General Hospital used 15 drops (90 mg) of Lugol daily for the treatment of exophthalmic goiter, with a 92% success rate, eliminating the need for surgery.
"Exophthalmic goitre of Graves' disease." New Sydenham Society, London, 1868; 586.
"The use of Lugol's solution in exophthalmic goitre." Ann Surg, 1927; 86:871-876.
