exon

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ex·on

(ek'son),

A portion of DNA that codes for a section of the mature messenger RNA obtained from that DNA, and is therefore expressed ("translated" into protein) at the ribosome.

[ex- + on]

Farlex Partner Medical Dictionary © Farlex 2012

exon

(ĕk′sŏn)

A nucleotide sequence that is found in a gene, codes information for protein synthesis, and is transcribed to messenger RNA.

ex·on′ic adj.

ex·on

(ek'son)

A portion of a DNA that codes for a section of the mature messenger RNA from that DNA, and is therefore expressed ("translated" into protein) at the ribosome.

[ex- + on]

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

exon

The segment of deoxyribonucleic acid (DNA) in a gene that codes for some part of the messenger ribonucleic acid (RNA). Any segment that is represented in the RNA product. Segments that do not code for RNA are called introns.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

exon

extron

(‘ex'for expressed) or - the DNA segments of an INTERRUPTED split gene that are transcribed into RNA and then into the gene product. Exons occur along the length of the gene, and are separated by segments called INTRONS whose sequences are also transcribed into RNA. The intron RNA segments are then excised, leaving behind the exon RNA segments that join up to form a functional RNA molecule, a process called RNA SPLICING.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

References in periodicals archive ?

In the present case control study, a total of five SNPs three in the promoter region given (rs3020449, rs3020450, rs1271572) and two in the exonic region (rs1256049, rs4986938) of the ER-[beta] gene were selected (http://www.ncbi.nlm.

Impact of Genetic Variants in Estrogen Receptor-[beta] Gene in the Etiology of Uterine Leiomyomas

Kadeva et al., "A genome-wide analysis of putative functional and exonic variation associated with extremely high intelligence," Molecular Psychiatry, vol.

Analysis of Association of Genetic Markers in the LUZP2 and FBXO40 Genes with the Normal Variability in Cognitive Performance in the Elderly

Sequence analysis revealed fifteen polymorphic sites in amplified exonic and associated intronic region of Pit1 gene of Pakistani Sahiwal cattle breed.

Identification of Pit1 Gene Variants in Sahiwal Cattle of Pakistan

The mean sequence coverage depth of targeted exonic regions reached 80.7-fold (ranging from 68.3-fold to 92.2-fold), and the median depth was 63.4-fold (ranging from 54-fold to 73-fold).

Whole-Exome Sequencing-Based Mutational Profiling of Hepatitis B Virus-Related Early-Stage Hepatocellular Carcinoma

Pgc-1[alpha]-a, Pgc-1[alpha]-b, Pgc-1[alpha]-c, and Pgc-1[alpha]4 differ in their N-termini due to transcription starting within either the distal, alternative (exon 1b), or proximal (exon 1a) promoters and also due to alternative splicing of exon 1b to produce exon 1b', whereas NT-Pgc-1[alpha] and FL-Pgc-1[alpha] both contain the full exonic regions from 1b, 1b/, 1a, and 2 (Figure 2(a)).

Quercetin and Quercetin-Rich Red Onion Extract Alter Pgc-1[alpha] Promoter Methylation and Splice Variant Expression

Exonic single nucleotide polymorphism (SNP) was examined at whole genome level [26].

Identification of a Novel ENU-Induced Mutation in Mouse Tbx1 Linked to Human DiGeorge Syndrome

Screening of the DNA sequence flankings of rs7003908 (G>T) for enhancer motif, Exonic Splicing Enhancers (ESEs) and Intronic Splicing Enhancers (ISEs), and silencer motif, Exonic Splicing Silencers (ESSs) and Intronic Splicing Silencers (ISSs), by HSF 3 and SpliceAid 2 tools have shown almost same results.

XRCC5 VNTR, XRCC6 -61C>G, and XRCC7 6721G>T Gene Polymorphisms Associated with Male Infertility Risk: Evidences from Case-Control and In Silico Studies

By sequencing all the four products in all 221 patients (FET, FPD, and ET-PD) and 100 controls, no exonic variant was identified, while one exon-intron boundary variant (rs2241028) and one intron variant (rs2241027) were detected.

Mutation Analysis of HTRA2 Gene in Chinese Familial Essential Tremor and Familial Parkinson's Disease

No exonic variant was detected in the MSA patients; four were detected in 6 ALS patients, including P2L and S85R present in PD patients; however, P2L was present at about an equal frequency in controls without neurological disease and S85R was present in 1 patient and 0 controls.

MNRR1, a Biorganellar Regulator of Mitochondria

Krainer, "Listening to silence and understanding nonsense: exonic mutations that affect splicing," Nature Reviews Genetics, vol.

Syntool: A Novel Region-Based Intolerance Score to Single Nucleotide Substitution for Synonymous Mutations Predictions Based on 123,136 Individuals

None of the identified SNPs were exonic or in linkage disequilibrium with exonic SNPs.

Prenatal air pollution exposures, DNA methyl transferase genotypes, and associations with newborn LINE1 and alu methylation and childhood blood pressure and carotid intima-media thickness in the children's health study

Note that this analysis does not include other categories of mutation, e.g., intronic splice variants, frameshifts, stop codons, etc., and that no other missense exonic splice variants have been found.

Missense splice variant (g.20746A>G, p.Ile183Val) of interferon gamma receptor 1 (IFNGR1) coincidental with mycobacterial osteomyelitis--a screen of osteoarticular lesions