exfoliative cytology


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cytology

 [si-tol´o-je]
the study of cells, their origin, structure, function, and pathology. adj., adj cytolog´ic.
aspiration biopsy cytology (ABC) the microscopic study of cells from superficial or internal lesions obtained by aspiration biopsy.
exfoliative cytology microscopic examination of cells desquamated from a body surface or lesion, done to detect malignancy or microbiologic changes, to measure hormonal levels, and for other purposes. The cells may be obtained by such procedures as aspiration, washing, smear, and scraping, and the technique may also be applied to secretions such as sputum, urine, abdominal fluid, prostatic secretions, and vaginal secretions.

ex·fo·li·a·tive cy·tol·o·gy

the examination, for diagnostic purposes, of cells denuded from a neoplasm (or other type of lesion) and recovered from the sediment of the exudate, secretions, or washings from the tissue (for example, sputum, vaginal secretion, gastric washings, urine).
Synonym(s): cytopathology (2)

ex·fo·li·a·tive cy·tol·o·gy

(eks-fō'lē-ă-tiv sī-tol'ŏ-jē)
The examination, for diagnostic purposes, of cells denuded from a neoplasm or an epithelial surface, recovered from exudate, secretions, or washings from tissue (e.g., sputum, vaginal secretion, gastric washings, urine).
Synonym(s): cytopathology (2) .

exfoliative cytology

A method of diagnosing cell abnormalities, such as cancer, by examining cells shed, brushed or scraped from a body surface.
References in periodicals archive ?
Clinicopathological correlation of micronucleus in oral squamous cell carcinoma by exfoliative cytology. J Oral Maxillofac Pathol 2008;12:2-7.
[1,16] These findings, which demonstrate the lack of efficiency of exfoliative cytology, may be explained by nonrepresentative sampling and/or individual subjectivity, [12,15] since this was a retrospective study in which the cytological tests were not performed by the same examiner.
Moreover it is emphasized that traditional exfoliative cytology has its limitations nonetheless introduction of special techniques like computer assisted oral brush biopsy and liquid based cytology have shown much better sensi- tivity and less false negative results and oral cytology seems promising to be used as a screening test like that used in cervical smears in near future.
However, children in the EG showed more yeasts adhering to their epithelial cells in the exfoliative cytology examination.
Overall, the results of this study suggest that, GFNAC system, with its employment restricted to exfoliative cytology, it cannot be a substitute for CFAC in the cytodiagnosis of breast lumps, though it has a high sensitivity; but due to its low sensitivity and complexity.
George Papanicolaou and colleagues published their research with exfoliative cytology samples of the breast in 1958.
For this reason, many urologists use an adjunctive diagnostic procedure, such as exfoliative cytology. Cytology, however, has several disadvantages, including its reliance for accuracy on the skill of the pathologist, its relative insensitivity to grade I (well-differentiated) tumors, and a lack of standardization of methods (7, 8).
When the discipline of exfoliative cytology was first launched in the late 1940s, the primary purpose of the Papanicolaou smear was to detect cervical cancer, which at that time was a scourge, almost the equal of breast cancer.
Diagnosis of lung cancer by aspiration biopsy and a comparison between this method and exfoliative cytology. Acta Cytol 1967;11(2):114-9.
[4] However, exfoliative cytology of oral mucosa is an effective and rapid procedure which can also be done for detection of granulomatous lesions.
One of the main advantages of cytology is that, for both primary diagnosis and clinical staging, specimens can be obtained with many minimally invasive techniques, including superficial aspirations, computed tomography-guided aspirations, ultrasound-guided aspirations, endoscopic ultrasound-guided aspirations, and collection of body fluids and brushings (exfoliative cytology).
Different diagnostic methods such as routine histopathology (H and E-stained sections), exfoliative cytology, and immunohistochemistry are available today.