As with exertional rhabdomyolysis
, hematuria can rise from metabolic and/or environmental factors such as dehydration, strenuous exercise, and acidosis.
Although the overall effects of SCT are benign, many studies and case reports have identified that individuals with SCT are at an increased risk for rare conditions including exertional rhabdomyolysis
with prolonged physical activity, compartment syndrome, and sudden cardiac death .
Fortin, "Bilateral, exercise-induced thigh compartment syndrome diagnosed as exertional rhabdomyolysis
. A case report and review of the literature," American Journal of Sports Medicine, vol.
Compared to 0.8 percent of the soldiers without sickle cell trait who developed exertional rhabdomyolysis
, just over 1 percent of black soldiers with the trait developed the condition, Kurina said.
We report the case of a young, active duty SCT positive African American male presenting with exertional rhabdomyolysis
complicated by myoglobinuric renal failure requiring hemodialysis.
Reasonableness and foreseeability are central to a legal analysis of exertional rhabdomyolysis
. The concern is whether rhabdomyolysis is a reasonably foreseeable consequence of strenuous or prolonged exertion during exercise and sports events.
in a bodybuilder following overexertion: a possible link to creatine overconsumption.
Muldoon, "Exertional rhabdomyolysis
and malignant hyperthermia in a patient with ryanodine receptor type 1 gene, L-type calcium channel a-1 subunit gene, and calsequestrin-1 gene polymorphisms," Anesthesiology, vol.
The policy resulted from a legal settlement with the family of Dale Lloyd II, a Rice University football player, who collapsed during football practice and later died from acute exertional rhabdomyolysis
attributed to SCT (Figure 1).
But as the diagnosis emerged - exertional rhabdomyolysis
- the questions lingered: How did it happen?
Leading causes of non-traumatic, non-cardiac sports death are exertional hyperthermia, followed by exertional rhabdomyolysis
and status asthmaticus.
Eichner opened the meeting with the keynote address on exertional rhabdomyolysis
. In additional presentations, he discussed sickle cell trait and sudden death and strategies for the exertional cramper.