Toxins that bind to certain receptors (for example, certain glutamate receptors) and may cause neuronal cell death; excitotoxins may be involved in brain damage associated with strokes.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Typically, the exposure to the pathogen is minute and without the risk of artificial excitotoxins as is the case with artificial means of attempted immunity.
Monosodium glutamate (MSG) and aspartame act as excitatory neurotransmitters (excitotoxins), which have the potential to damage neurons and cause symptoms in susceptible individuals.
Obal et al., "Mental disturbances in Parkinson's disease and related disorders: the role of excitotoxins," Journal of Parkinson's Disease, vol.
Toxic effects of putrescine in rat brain: Polyamines can be involved in the action of excitotoxins. Amino Acids.
The triggered innate immune response (e.g., proinflammatory cytokines, chemokines, reactive oxygen species, excitotoxins, histamine, and prostaglandins) has detrimental influences on the neurons, oligodendroglial precursors, and vascular endothelial cells.
Coyle, "Idebenone attenuates neuronal degeneration induced by intrastriatal injection of excitotoxins," Experimental Neurology, vol.
Simon, "A potential role for excitotoxins in the pathophysiology of spinal cord injury," Annals of Neurology, vol.
(16) Lithium's ability to stimulate neural stem cell production may prove to be of significant benefit in individuals recovering from spinal cord injury and neurological injuries caused by severe trauma (TBI, traumatic brain injury), dietary and environmental excitotoxins (mercury, aspartame, monosodium glutamate), and substance abuse.
In this regard, dietary excitotoxins including aluminum can exacerbate the clinical presentation by worsening of excitotoxicity and by microglial priming.
added to our concerns about the toxicity of aspartame with his book 'Excitotoxins: The Taste That Kills.' At the same time new sweeteners such as Splenda have been introduced that claim to be harmless, yet critics disagree.