The nAChR responds to neurotransmitter stimulation by allowing rapid influx of sodium, producing an excitatory postsynaptic potential.
This causes the excitatory postsynaptic potential to stimulate either QA or KA receptors, which in turn activate additional NMDA receptor sites, thereby enhancing the excitatory potential of the initial signal.
Keywords: Centella asiatica Asiatic acid Acetylcholinesterase
Excitatory postsynaptic potential Locomotor activity
After stability of the recording had been obtained [recording for at least 30 min after mounting and a population field
excitatory postsynaptic potential (fEPSP) of constant amplitude], we recorded control responses and applied tetanic stimuli consisting of two separate 1-sec stimulations, each at the test intensity at 100 Hz with the two stimulations separated by 5 sec.
As shown by Armitage and Siegelbaum (1998), short-term homosynaptic depression of the in vitro sensorimotor synapse proceeds normally with repeated activation of the sensory neuron despite a blockade of (presumably) postsynaptic glutamate receptors by DNQX sufficient to eliminate the sensorimotor
excitatory postsynaptic potential (EPSP).
Hussain and colleagues monitored the amplitude of the field
excitatory postsynaptic potential (fEPSP), which reflects the intensity of the response of hippocampal neurons to stimulation.
Methods: Field
excitatory postsynaptic potentials (fEPSPs), spontaneous excitatory postsynaptic currents (sEPSCs) and miniature spontaneous excitatory postsynaptic currents (mEPSCs) were recorded, by using in vitro field potential electrophysiology and whole-cell patch clamp techniques in acute hippocampal slices from rats.
Calcium dynamics in single spines during coincident pre- and postsynaptic activity depend on relative timing of back-propagating action potentials and subthreshold
excitatory postsynaptic potentials.
Therefore, in the present study we tested whether TDE can modulate dendritic field
excitatory postsynaptic potentials (fEPSPs), which indicate the neuronal synaptic function, in Cornu Ammonis 1 (CA1) hippocampal slices of normal rats as found in current AChE-I drugs used for AD therapy.
These APs propagate to synapses and elicit
excitatory postsynaptic potentials (EPSPs).
This increase in L-type channels is correlated with increased failure of
excitatory postsynaptic potentials as well as increased susceptibility to cell death.
Impulses of specific small-cell axons can be correlated with
excitatory postsynaptic potentials (EPSPs) recorded intracellularly from large-cell somata (Fig.
