excitation-contraction coupling

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an act of irritation or stimulation; a condition of being excited or of responding to a stimulus; the addition of energy, as the excitation of a molecule by absorption of photons.

in the stimulation of muscle contraction this is the coupling which occurs at the sarcolemma-sarcoplasmic reticulum junction. Mediated by the release of calcium ions in the aqueous sarcoplasm.
excitation-contraction coupling
conversion of an excitation stimulus into contraction of the effector muscle fiber; ionic calcium is the link between the two.
indirect excitation
electrostimulation of a muscle by placing the electrode on its nerve.
in the stimulation of muscular contraction this is the stimulation of secretion of acetylcholine from the vesicles in the cholinergic nerve terminals into the synaptic cleft at the nerve-muscle junction.
excitation signs
see irritation nervous signs.
References in periodicals archive ?
Similarly, Tarnopolsky [43] reported that caffeine delayed the fatigue in human muscle during low-frequency stimulation, demonstrating an impact of caffeine on excitation-contraction coupling.
Due to non-genomic rapid increases in intracellular calcium levels and increased mobilisation of calcium from the sarcoplasmic reticulum, testosterone may reduce or protect against impaired excitation-contraction coupling during repeated high-intensity muscle contraction.
2:10 "Influence of IGF-1 supplementation on cardiac excitation-contraction coupling in diabetes.
Several mechanisms, such as neuromuscular propagation, excitation-contraction coupling, intracellular regulation, might be responsible for the decreases observed in evoked contractions and MVC (Bigland-Ritchie, 1984; Hill et al.
1:30 "Characterization of excitation-contraction coupling in diabetic hypertensive cardiomyopathy in adult rat ventricular myocytes," Loren Wold *, David Relling, and Jun Ren, Department of Pharmacology, Physiology & Therapeutics, University of North Dakota, Grand Forks.