excipient


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vehicle

 [ve´ĭ-k'l]
2. any medium through which an impulse is propagated.

ex·cip·i·ent

(ek-sip'ē-ent),
A more or less inert substance added in a prescription as a diluent or vehicle or to give form or consistency when the remedy is given in pill form; for example, simple syrup, vegetable gums, aromatic powder, honey, and various elixirs.
[L. excipiens; pres. p. of ex- cipio, to take out]

excipient

(ĭk-sĭp′ē-ənt)
n.
An inert substance used as a diluent or vehicle for a drug.

ex·cip·i·ent

(ek-sip'ē-ĕnt)
A more or less inert substance added in a prescription as a diluent or vehicle or to give form or consistency when the remedy is given in pill form.
[L. excipiens; pres. p. of ex-cipio, to take out]

excipient

Any inert substance used to bulk up or dilute a drug, or as a vehicle for a drug.

ex·cip·i·ent

(ek-sip'ē-ĕnt)
A more or less inert substance added in a prescription as a diluent or vehicle or to give form or consistency when the remedy is given in pill form; e.g., simple syrup, vegetable gums, aromatic powder, honey, and various elixirs.
[L. excipiens; pres. p. of ex-cipio, to take out]
References in periodicals archive ?
At 40[degrees]C [+ or -] 1[degrees]C under dry conditions, AMLO and OLME, after 3 and 6 months, did not present changes in concentration recovery in binary and ternary mixtures, indicating that in dry conditions, the AMLO and OLME are compatible with the excipients in the studies.
The main objectives of the present study were to improve the apparent solubility of itraconazole (ITR) and to test the proposed hypothesis of using sacrificial amorphous excipients for imparting dissolution stability to APIs during storage.
Formalization of good manufacturing practices for excipients is an urgent need in the global excipients market, in order to cater to rising demand for higher purity excipients in applications such as parenteral forms.
In this investigation since a given tablet formulation was compressed under confined machine settings, it follows that the number of sites available for bonding in a given concentration of an excipient in a formulation is the sole working parameter.
The physicochemical and the pharmacokineticdynamic properties of the drug substance determine if functional excipients and applied technology are required to achieve the desired drug concentration at the site of action.
Alternative drug delivery technologies may be required to meet bioavailability requirements, and different excipients or levels could be necessary to meet safety profile requirements.
Factors such as the growing pharmaceutical market with the rapidly aging population and increasing incidence of chronic disease, advancements in functional excipients, growing generics market propelled by the patent cliffs, and the rapidly growing biopharmaceuticals sector are driving the growth of the pharmaceutical excipients market.
Each tablet was made to contain 200 mg metronidazole, 300 mg direct compression excipient, and 2.5 mg each of talc and magnesium stearate.
As a consequence, excipient samples containing water [less than or equal to] 20% (w/w) can be analyzed without any significant effects on formaldehyde determination.
The development of any pharmaceutical form necessitate the complete study of different levels of excipients used in various formulations in order to identify the exact proportion of what maximizes quality and stability of the final product.
Boston, MA, September 22, 2016 --(PR.com)-- Excipients are a broad range of non-active components combined with active pharmaceutical ingredient (API) during formulation to form a desired finished drug product and perform a wide range of functions.
In this study, DMA was cured into a silicone matrix at 5%, 10% and 15% concentrations (m/m) along with varying concentrations of excipient A (0-20%) or excipient B (0-12%), The silicone sample was placed in a simulated physiological environment and HPLC analysis was conducted daily on the eluent, allowing quantification of drug release into the physiological solution on a daily basis over 14 days.