Acute respiratory distress syndrome and non-occlusive mesenteric ischemia as major clinical manifestations of thrombotic thrombocytopenic purpura: Complete remission following exchange plasmapheresis
. J Clin Apher 1998;13(4):190-192.
Treatment of thrombotic thrombocytopenic purpura with exchange plasmapheresis and methylprednisolone was of paramount importance and the patient was discharged home on day 30 with complete recovery of haematological, neurological and renal function.
We review the diagnostic challenges, emphasising that early recognition and treatment with exchange plasmapheresis is of paramount importance for a favourable outcome.
Current treatment options for HELLP syndrome include administration of plasma volume expansion, thrombolytic agents, immunosuppressive agents, and exchange plasmapheresis
. If immunosuppressive agents are used to treat HELLP syndrome, "I think it's important to stick to recommendations of IV, not IM, dexamethasone," he said.