Approximately 20% of bipolar patients are thought to experience rapid cycling, defined as [greater than or equal to]4 affective episodes/year separated by at least 2 weeks of euthymia
between poles or with an immediate switch from one pole to the other.
If ADHD symptoms persist during euthymia
, additional treatment may be indicated.
If there is a single critical guiding principle for the clinician when it comes to managing bipolar women during pregnancy and the postpartum period, it is sustaining euthymia
. With the recent focus of the U.S.
The Hamilton Depression Rating Scale (HDRS) and the Young Mania Rating Scale (YMRS) were used for all studies to determine the status of euthymia
, except for one that used the Montgomery-Asberg Depression Scale to measure depression with a cut-off point of <10.
Stella Stabouli[C], (1) Euthymia
Vargiami, (1) Olga Maliachova, (1) Nikoleta Printza, (1) John Dotis E,1) Maria Kyriazi, (1) Konstantinos O.
Keywords: Bipolar disorder, euthymia
, lithium, valproic acid, atypical antipsychotic
When patients with bipolar disorder are first seen in the office, their state may be depression, mania, hypomania, or even euthymia
. Keep in mind that the first 3 aberrations may indicate other disorders, either psychiatric (TABLE 1) (1,4) or medical (eg, hyperthyroidism, delirium).
(13) Growing evidence suggests that bipolar disorder patients experience prominent neurocognitive impairment not only during acute mood episodes (14,15) but also during euthymia
. (16,17) The cognitive deficits intrinsic to bipolar disorder itself typically coalesce around problems with attentional processing, executive function, and verbal memory.
Sleep disturbances are also prevalent during euthymia
, indicating that sleep is still affected after mood has stabilized .
Bech, "The Concept of Euthymia
," Psychotherapy and Psychosomatics, vol.
Birner et al., "Mood stabilizers, oxidative stress and antioxidative defense in euthymia
of bipolar disorder," CNS & NuerologicalDisorders--Drug Targets, vol.