Although published dosages for psittacine birds are 0.002-3 IU/kg IM q 12h of neutral protamine Hagedorn insulin, and a toco toucan was treated with [is less than or equal to] 2 IU IM of PZI, this Bali mynah did not approach
euglycemia until it received 8-10 IU/kg of compounded PZI.
* P < 0.05 as compared with
euglycemia group; # P < 0.05 as compared with hyperglycemia group.
Most of the cases developed hypoglycemia in the first hour of life, so screening for high risk neonates should be done at 1hr, 2hrs, 4hrs, 6hrs, 12hrs, 24hrs, 48hrs, and 72hrs of life or maintaining
euglycemia with oral feeds.
The use of other agents in combination with insulin, such as glucagon-like peptide-1 (GLP1) analogue exenatide, has shown to reduce the amount of insulin required to achieve
euglycemia [4].
Intensive insulin therapy aiming at
euglycemia improves their clinical outcome [3-5].
Vaccinia virus-delivered immunomodulated autoantigens and CFA may provide continuous suppression of diabetes inflammation, thereby establishing an alternative approach for repopulation of the pancreas with "beta-like" insulin secreting cells, which could establish an effective and durable interventional therapy for restoration of
euglycemia and immunological homeostasis in the large population of patients currently suffering from type 1 diabetes.
The hyperinsulinemic glucose clamp was used in both studies to establish
euglycemia and hypoglycemia on separate occasions [5.2 mmol/L (94 mg/dL) and 4.5 mmol/L (81 mg/dL), respectively, during euglycemic clamps, and 2.9 mmol/L (52 mg/dL) and 2.5 mmol/L (45 mg/dL), respectively, during hypoglycemic clamps].
Normal levels of [HbA.sub.1c] in nondiabetic patients indicate that even
euglycemia and/or brief periods of hyperglycemia cause glycosylation of hemoglobin A and result in accumulation over time.
The five precautions are [beta]-adrenergic blockade,
euglycemia, deep-vein thrombosis prophylaxis, prophylactic antibiotics, and normothermia.
Near
euglycemia can be safely pursued with insulin therapy in patients with type 2 diabetes.
The
euglycemia that is present in these athletes at rest is probably also mediated by irisin.
IRS in patients with R-T1D was defined as necessity for insulin therapy in order to accomplish
euglycemia (fasting glycemia <5,5mmol/L, postprandial glycemia <10.0 mmol/L).
