etomidate


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etomidate

 [ĕ-tom´ĭ-dāt]
a sedative and hypnotic, administered intravenously for induction and maintenance of general anesthesia and as a supplement to low-potency anesthetics for maintenance of anesthesia during short operative procedures.

etomidate

/etom·i·date/ (ĕ-tom´ĭ-dāt) a sedative-hypnotic, administered intravenously for the induction and maintenance of anesthesia.

etomidate

[etom′idāt]
a short-acting, hypnotic nonbarbiturate IV agent used for induction of general anesthesia. It has minimal adverse cardiovascular and respiratory effects, thus providing a greater margin of safety in patients with or at risk for heart disease. Adverse effects include transient reduction in adrenal gland cortisol release, pain on injection, and involuntary muscle movements.

etomidate

A general anaesthetic drug. A brand name is Hypnomidate.

etomidate

an intravenous, nonbarbiturate, fast-inducing anesthetic with no analgesic effect. Also causes suppression of adrenal steroidogenesis and may be used in the treatment of hyperadrenocorticism.
References in periodicals archive ?
Comparison of Etomidate and Ketamine for Induction During Rapid Sequence Intubation of Adult Trauma Patients.
Fifty-three-old Mark Asay was reportedly executed using etomidate as one of three drugs in the lethal injection.
Several other accidental intraarterial anesthetics injections have been published, although ischemic and necrotic changes were reported with high lipid-soluble drugs such as propofol, diazepam, and etomidate (2).
Background: Propofol and etomidate are the most important intravenous general anesthetics in the current clinical use and that mediate gamma-aminobutyric acid's (GABAergic) synaptic transmission.
Intravenous anesthetics which are safe to be used in anesthesia are propofol, ketamine and etomidate because of their minimal effect on neuromuscular transmission.
Two agents were found not to induce aversive behavioral responses: etomidate and 2,2,2 tribromoethanol.
Though not a novel drug, etomidate challenges all algorithms prevalent in the field of anesthesia over the last 10 years.
2] In addition, etomidate has prolonged recovery time with high incidence of pain on injection, myoclonic activity, and heavy cost.
The main treatment modalities include hyperosmolar therapy, temperature control, consideration of etomidate to control severe increased ICP and thiopental to control ICP, and consideration of prophylactic treatment to reduce incidence of early posttraumatic seizures (PTSs).
Etomidate is perhaps one of the most immunologically safe anesthetics.