etomidate


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etomidate

 [ĕ-tom´ĭ-dāt]
a sedative and hypnotic, administered intravenously for induction and maintenance of general anesthesia and as a supplement to low-potency anesthetics for maintenance of anesthesia during short operative procedures.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

etomidate

A general anaesthetic drug. A brand name is Hypnomidate.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Emergency and prolonged use of intravenous etomidate to control hypercortisolemia in a patient with Cushing's syndrome and peritonitis.
[2] In addition, etomidate has prolonged recovery time with high incidence of pain on injection, myoclonic activity, and heavy cost.
The main treatment modalities include hyperosmolar therapy, temperature control, consideration of etomidate to control severe increased ICP and thiopental to control ICP, and consideration of prophylactic treatment to reduce incidence of early posttraumatic seizures (PTSs).
Etomidate is perhaps one of the most immunologically safe anesthetics.
Some of Zydus' recent launches include potassium chloride extended-release tablets 8mEq, etomidate injection, morphine sulfate extended-release tablets, isosorbide mononitrate extended-release tablets, and pyridostigmine bromide tablets.
In addition, the imidazole ring system is one of the most important substructures found in a large number of natural products and pharmacologically active compounds, such as the hypnotic agent etomidate [5].
There are numerous intravenous drugs available for inducing sedation and analgesia prior to cardioversion, including Etomidate, fentanyl, midazolam, Propofol, Thiopental, and Methohexital [4].
In February, Mylan recalled 10 lots of the injectable "hypnotic drug" etomidate in 2-, 10- and 20-mL doses because pieces of shredded labels were found in some vials.
Effects of etomidate on blood cortisol insulin and glucose levels and PONV rates in smokers.
Midazolam is more likely to cause hypotension than etomidate in emergency department rapid sequence intubation.
etomidate, ketaconazole and rifampin) are involved in cortisol suppression through 11-* hydroxylase enzyme inhibition, interfering with last step in active cortisol synthesis, and causing adreno-cortical insufficiency [17, 22], that might explain some of the actions observed in RAO aged horses treated with FP.
Anesthetic agents with minimal effects on myocardial contractility and SVR like etomidate are preferred while propofol and sodium pentothal having the exact opposite effects should be avoided for induction [50, 51].