ethosuximide


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ethosuximide

 [eth″o-suk´sĭ-mīd]
an anticonvulsant used in the treatment of petit mal epilepsy; administered orally.

ethosuximide

Neurology An anticonvulsant used for absences Adverse effects BM suppression, aplastic anemia. See Epilepsy, Seizures.

ethosuximide

An antiepileptic drug used in the management of absence attacks (Petit mal). It has no effect against major EPILEPSY and may cause nausea and drowsiness. The drug is on the WHO official list. Brand names are Emeside and Zarontin.
References in periodicals archive ?
Table Drugs that can cause akathisia * Dopamine receptor agonists (such as antiparkinsons agents) * Carbidopa/levodopa * Ethosuximide * Metoclopramide * Neuroleptics * Reserpine * Selective serotonin reuptake inhibitors
Seizure medications: phenytoin, carbamazepine, primidone, ethosuximide, methylphenobarbital, paramethadione, phenobarbital, topiramate
The most commonly used drugs are carbamazepine (Calepsin[R]), benzodiazepines (for example, clonazepame [Klonopin[R]]), barbiturates (for example, phenobarbital [Luminal[R]]), primidone (Mysoline[R]), phenytoin (Dilantin[R]), ethosuximide (Zarontin[R]), gabapentin (Neurontin[R]), tiagabine (Gabitril[R]), topiramate (Topamax[R]), and valproate (Depacon[R]) (Glauser et al., 2006; Ropper & Brown, 2005).
At the time of his admission to the inpatient facility, he was on several medications including valproic acid, clonazepam, felbamate, ethosuximide, and sertraline.
The subsequent chapters provide details on specific drugs: aminoglycosides, vancomycin, digoxin, lignocaine, procainamide, quinidine, phenytoin, carbamazepine, valproate, phenobarbitone, ethosuximide, cyclosporin, tacrolimus, lithium and theophylline.
Drug concentrations were as follows: phenytoin, 15.2 mg/L; phenobarbital, 30.3 mg/L; primidone, 7.1 mg/L; carbamazepine, 7.7 mg/L; carbamazepine 10,11-epoxide, 1.9 mg/L; ethosuximide, 68.1 mg/L; valproate, 76.8 mg/L; clonazepam, 42.0 [micro]g/L; lamotrigine, 3.1 mg/L; theophylline, 15.0 mg/L; caffeine, 7.8 mg/L; digoxin, 1.2 [micro]g/L; gentamicin, 2.7 mg/L; and lithium 0.76, mmol/L.
Although most of the drugs had no effect or were toxic to the worms, Kornfeld's team found that ethosuximide, an anticonvulsant drug, increased the worms' life span by 17 percent.
ampicillin (Polycillin) ciprofloxacin (Cipro) Anticonvulsants: Act on the central nervous ethosuximide (Zarontin) system to reduce number fosphenytoin (Cerebyx) and severity of seizures.
Parameters Used in Calculation of Imprecision Limits(*) Therapeutic Drug Therapeutic Range [t.sub.1/2] Range, h Carbamazepine, [micro]mol/L ([micro]g/mL) 16.9 (4)-50.8 (12) 12-17 Digoxin, nmol/L (ng/mL) 1.0 (0.8)-2.6 (2.0) 36-48 Ethosuximide, [micro]mol/L ([micro]g/mL) 283 (40)-708 (100) 56-60 Lithium, mmol/L 0.5-1.0 24-24 N-Acetylprocainamide, [micro]mol/L ([micro]g/mL) 36.1 (10)-108 (30) ...
Q MY grand-daughter, who is eight, has been prescribed 250mg per day of Ethosuximide for the non-fit type of epilepsy she has.
Standard therapies in children include carbamazepine, phenobarbital, ethosuximide, phenytoin, valproic acid, prednisone, and adrenocorticotrophic hormone.