ethinyl estradiol


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ethinyl

 [eth´ĭ-nil]
the radical HC≡C—, derived from acetylene.
ethinyl estradiol an estrogen derived from estradiol, used together with a progestational agent as a component of many oral contraceptives, in hormone replacement therapy, and as an antineoplastic in the treatment of advanced breast and prostate cancers; administered orally.

e·thy·nyl es·tra·di·ol

a semisynthetic derivative of 17β-estradiol; active by mouth, with a long half-life, it is among the most potent of known estrogenic compounds; used in oral contraceptive preparations.
Synonym(s): ethinyl estradiol

ethinyl estradiol

(ĕth′ə-nĭl′)
n.
A synthetic estrogen derivative, C20H24O2, used in oral and other contraceptive preparations and in hormone replacement therapy, usually in combination with a progestin.

Ethinyl estradiol

A semi-synthetic derivative of estradiol—an estrogen or female sex hormone—used in birth control pills and combined ECPs.
References in periodicals archive ?
Comparison of efficacy and safety of metformin, oral contraceptive combination of ethinyl estradiol and drospirenone alone or in combination in polycystic ovarian syndrome.
Efficacy, acceptability and tolerability of the combined contraceptive ring, NuvaRing, compared with an oral contraceptive containing 30 microg of ethinyl estradiol and 3 mg of drospirenone.
In another earlier study, 18 healthy premenopausal women were treated with a low-dose OC pill of 0.02 mg ethinyl estradiol and 0.150 desogestrel either alone during the control cycle or combined with St.
(8) And the major NNRTI alternative to nevirapine--efavirenz--was found to increase levels of ethinyl estradiol in unpublished studies conducted by the drug manufacturer.
More recently, in the December 2004 issue of EHP, Jon Nash and colleagues showed that long-term laboratory exposure to environmental concentrations of the pharmaceutical ethinyl estradiol caused reproductive failure in zebrafish.
One group received additional ethinyl estradiol on days 22-28, which is the typical placebo week of the oral contraceptive pills.
In the early 1970s, reports appeared in the literature confirming the safety and efficacy of a combination of ethinyl estradiol and levonorgestrel as a pregnancy interceptive.[4,5] Failure rates have been reported ranging from zero to five percent, with the majority of studies indicating a failure rate of approximately 1.5 percent to two percent.[6,7,8,9] Two tablets containing 50,[Mu]g of ethinyl estradiol and 250,[Mu]g of levonorgestrel per tablet are administered at once, followed by two tablets 12 hours later.
This unique contraceptive vaginal system technology combines low doses of a novel progestin, Nestorone (segesterone acetate), with a widely used estrogen (ethinyl estradiol).
Pharmaceutical company Mylan NV (NASDAQ:MYL) revealed on Wednesday the availability of Drospirenone and Ethinyl Estradiol Tablets USP in 3 mg/0.02 mg in the US contraceptive market.
Any OEP is better than no OEP, regardless of the progestin used to treat the PCOS because ethinyl estradiol plus any synthetic progestin suppresses pituitary secretion of LH and decreases ovarian androgen production.
USA, a subsidiary of Glenmark Pharmaceuticals Ltd., says it has received approval from the Food and Drug Administration of the Abbreviated New Drug Application (ANDA) for its generic levonorgestrel and ethinyl estradiol tablets USP (0.09 mg/0.02 mg), which are the therapeutic equivalent of Wyeth's Lybrel, a combination of female hormones that prevents ovulation.
SAN DIEGO - Women who were randomized to an investigational low-dose ethinyl estradiol and levonorgestrel contraceptive patch had similar contraceptive efficacy, cycle control, and safety results, compared with those who were randomized to a standard oral contraceptive containing 20 mg ethinyl estradiol and 0.1 mg levonorgestrel, results from a phase III trial demonstrated.