ethambutol


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ethambutol

 [ĕ-tham´bu-tol]
an antibacterial agent specifically effective against Mycobacterium tuberculosis; it is administered orally as the hydrochloride salt, in conjunction with one or more other antituberculous drugs, in the treatment of pulmonary tuberculosis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ethambutol

(ĕ-thăm′byə-tôl′, -tōl′, -tŏl′)
n.
An antibacterial drug, C10H24N2O2, used in a hydrochloride form with other drugs to treat pulmonary tuberculosis.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

ethambutol

Myambutol AIDS A combination therapy agent used to treat TB and MAC Adverse effects ↓/distorted vision, pain and swelling of joints, burning pain, N&V, headache, mental confusion Contraindications Ethambutol should not be given to children too young to be monitored for changes in vision. See AIDS.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

ethambutol

A drug used, ideally in combination with other drugs, in the treatment of TUBERCULOSIS. Ethambutol can cause damage to the optic nerves and if persisted with after vision is affected can cause blindness. Also known under the generic name of myambutol. The drug is on the WHO official list.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
EMB, ethambutol; INH, isoniazid; MDR, multidrug resistant; mono, monoresistant; RIF, rifampin; SM, streptomycin; XDR, extensively drug resistant.
Further, in isolation, streptomycin showed highest resistance of 4.6% followed by rifampicin 4.0%, isoniazid 3.7% and ethambutol 1.9%.
Visual evoked potentials in the detection of subclinical optic toxic effects secondary to ethambutol. Arch Neurol 1983;40:645-8.
We compared moxifloxacin based regimen (combination of isoniazid, rifampin, pyrazinamide, moxifloxacin) with standard treatment (combination of isoniazid, rifampin, pyrazinamide, ethambutol) for TBM.
Abbreviations CNS: Central nervous system ETH: Ethambutol INH: Isoniazid MDR-TB: Multidrug resistant tuberculosis Moxi: Moxifloxacin NAT: Nucleic acid testing PCR: Polymerase chain reaction PHESS: Public Health Event Surveillance System PZE: Pyrazinamide RIF: Rifampicin TB: Tuberculosis XDR-TB: Extensively drug resistant tuberculosis.
Although Ethambutol also has been reported to cause AKI [16], it is more commonly known to cause ocular optic neuropathy [17].
He had also received 4 months of INH and 2 months of ethambutol, which may not have significantly contributed to his resolution.
Safi H, Fleischmann RD, Peterson SN, Jones MB, Jarrahi B, AllandD.Allelic exchange and mutant selection demonstrate that common clinical embCAB gene mutations only modestly increase resistance to ethambutol in Mycobacterium tuberculosis.
Diagnosis of drug resistance to fluoroquinolones, amikacin, capreomycin, kanamycin and ethambutol with genotype MTBDRsl assay: A meta-analysis.
tuberculosis for susceptibility against isoniazid, rifampicin, ethambutol, and streptomycin.
MDR, KMRC 00116-00250, pathogenic-resistant to isoniazid, rifampicin, streptomycin, and pyrazinamide; XDR, KMRC 00203- 00197, pathogenic-resistant to isoniazid, rifampicin, ethambutol, kanamycin, ofloxacin, rifabutin and amikacin, but susceptible to capreomycin, streptomycin, moxifloxacin, prothionamide, p-aminosalicylic, and cycloserine.
Fifty-five Thai patients with tuberculosis were randomly assigned to receive, in double-blind fashion, 140 mg of silymarin 3 times per day or placebo, in addition to a standard antituberculosis treatment regimen of isoniazid (5 mg/kg/day), rifampicin (10 mg/ kg/day), pyrazinamide (25 mg/kg/day), and ethambutol (15 mg/ kg/day).