estriol


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Related to estriol: estradiol, estrone

estriol

 [es´tre-ol]
a relatively weak human estrogen that is a metabolic product of estradiol and estrone found in high concentration in the urine of females.

es·tri·ol

(es'trē-ol),
An estrogenic metabolite of estradiol, usually the predominant estrogenic metabolite found in urine (especially during pregnancy); epimers at C-16, C-17, or both, are known as 16-epiestriol, 16,17-epiestriol, and 17-epiestriol.

estriol

(ĕs′trī-ôl′, -ōl′, -ŏl′, ĕ-strī′-)
n.
An estrogenic hormone, C18H24O3, that is a metabolite of estradiol and is present chiefly during pregnancy. It is produced by the placenta and is found in the urine of pregnant women.

oestriol

The weakest of the three natural human oestrogens; it only appears in significant amounts during pregnancy as it is produced by the placenta from 16-OH DHEA-S, an androgen produced by the foetal liver and adrenal glands.

Pronunciation
Medspeak-UK: pronounced, EE stree oll
Medspeak-US: pronounced, ESS tree oll

estriol

Physiology A steroid hormone, the synthesis of which depends on a sequence of biochemical reactions in the placenta or fetus in a functional compartment, the fetoplacental unit–FPU. See Triple marker.

es·tri·ol

(es'trē-ol)
An estrogenic metabolite of estradiol, usually the predominant estrogenic metabolite found in urine (especially during pregnancy).
Synonym(s): oestriol.
References in periodicals archive ?
In addition, the effects of the laser therapy remained statistically significant at the 12- and 18-month follow-ups, while the treatment effects of estriol were diminished at 12 months and, at 18 months, this group had some symptoms that were significantly worse than before treatment.
Preliminary results from the phase 2 clinical trial of sex hormone estriol [1] in women with MS show interesting results that call for further study.
Because MS is an autoimmune disorder in which the body essentially attacks itself, it's believed estriol is released during pregnancy to help suppress the immune system to prevent the body from treating the fetus as an invader.
The results from our method comparison were different from that depicted in the manufacturer's product insert (Siemens IMMULITE 2000 Unconjugated Estriol).
Among those laboratories, 56% (n = 169) offered AFP alone; 30% (n = 90) offered AFP, unconjugated estriol, and hCG (the triple test); and 14% (n = 42) offered AFP and hCG (the double test).
8,372,826: Estriol Therapy for Multiple Sclerosis and Other Autoimmune Diseases, which includes claims to Trimesta (oral estriol) in combination with glatiramer acetate injection (Copaxone).
Estriol (E3) is a specific type of estrogen, which is produced by the fetal placental unit.
Women's bodies naturally produce the hormones estrone, estradiol, estriol, and progesterone, and the hormones can also be produced in laboratories.
Multiple Sclerosis (MS) - Two Phase II Clinical Trials Ongoing Completed enrollment of 164 patients in a randomized, double-blind, placebo-controlled, multi-center Phase II clinical trial evaluating the efficacy and safety of our proprietary oral formulation of estriol (Trimesta) for the treatment of relapsing-remitting MS in women.