esthesioneuroblastoma


Also found in: Encyclopedia.

es·the·si·o·neu·ro·blas·to·ma

(es-thē'zē-ō-nū'ō-blas-tō'mă),
A neoplasm of immature, poorly differentiated neuronal cells believed to arise from neuroepithelial precursors.
[esthesio- + neuroblastoma]

esthesioneuroblastoma

A rare malignant neuroectodermal tumour of the nasal cavity in the retrobulbar region, middle cranial fossa, near the cribriform plate. It is thought to arise from the olfactory membrane of the sinonasal tract.

Clinical findings
Bimodal age distribution, affecting those in the 2nd and 6th decades of life; presents as a unilateral nasal obstruction, epistaxis, anosmia and headache, accompanied by nonspecific symptoms similar to other intranasal lesions—i.e., congestion, rhinorrhoea.
 
DiffDx
Small round cell malignancies that occur in the sinonasal tract—e.g., sinonasal undifferentiated carcinoma, lymphoma, rhabdomyosarcoma and neuroendocrine carcinomas.

Prognosis
5-year survival 50–60%; late recurrence is common. Hyams’ grading system is used for grading; it incorporates architecture, rosette formation, mitoses, necrosis and pleomorphism, and correlates with survival.

esthesioneuroblastoma

Olfactory neuroblastoma ENT A tumor of the nasal cavity, retrobulbar region or middle cranial fossa Clinical Nonspecific, similar to other intranasal lesions, ie congestion, rhinorrhea DiffDx Lymphoma, plasmacytoma, embryonal rhabdomyosarcoma Prognosis 5-yr survival 50-60%; late recurrence is common

esthesioneuroblastoma

see olfactory neuroblastoma.
Mentioned in ?
References in periodicals archive ?
Two patients with chordoma died from tumor aggression and two patients with esthesioneuroblastoma died from metastasis.
Endoscopic Approach to Remove Intra-extracranial Tumors in Various Skull Base Regions: 10-year Experience of a Single Center
Olfactory neuroblastoma (ONB), also known as Esthesioneuroblastoma, is a rare but distinct malignant neuroectodermal tumor arising from the olfactory epithelium of roof of nasal cavity and cribriform plate.
Olfactory neuroblastoma: A clinicopathological experience of a rare entity from Pakistan
Some histologies are staged using other systems, for example, the Kadish system is used for staging esthesioneuroblastoma.
Sinonasal neoplasms: Update on classification, imaging features, and management
SNUC can be distinguished from esthesioneuroblastomas by the histologic occurrence of intercellular fibrils and periodic Homer Wright rosettes in esthesioneuroblastomas.
Sinonasal undifferentiated carcinoma as a third primary neoplasm: a case report and review of the literature
Esthesioneuroblastoma : The Northwestern University experience.
Coexistencia de neuroblastoma olfatorio y aneurisma de la arteria carotida interna. Presentacion de un caso/ coexistence of an olfactory neuroblastoma and internal carotid artery aneurysm. Case report
Prognostic utility of Hyams histological grading and Kadish-Morita staging systems for esthesioneuroblastoma outcomes.
The Differential Diagnosis of Sinonasal/Nasopharyngeal Neuroendocrine/Neuroectodermally Derived Tumors
The differential diagnosis of lesions with this clinical apperance is very broad and includes epithelial neoplasm, esthesioneuroblastoma, meningioma, hemangiopericytoma, lymphoma, schwannoma, leiomyoma, angiofibroma, fibromatosis, malignant fibrous histiocytoma and fibrosarcoma.
Endoscopic resection of a rare case of solitary fibrous tumour of the nose and paranasal sinuses
Esthesioneuroblastoma is not a member of the primitive peripheral neuroectodermal tumour-Ewing's group.
Undifferentiated malignant neoplasms of the sinonasal tract
DISCUSSION: Olfactory neuroblastoma also called as Esthesioneuroblastoma is a relatively uncommon intranasal tumour that originates from the olfactory epithelium of the upper nasal cavity in the region of cribriform plate.
Esthesioneuroblastoma: a case report
Lesions included adnexal neoplasm, ameloblastic fibro-odontoma, basal cell carcinoma, benign fibrous histiocytoma, blue nevus, chondrosarcoma, compound nevus, epithelioma adenoides cysticum, esthesioneuroblastoma, Ewing sarcoma, fibrosarcoma, giant cell granuloma, granulocytic sarcoma, hemangioma, hemangiopericytoma, Langerhans cell histiocytosis, lymphangioma, lymphoma, melanoma, neuroblastoma, neurofibroma, ossifying osteofibroma, osteochondroma, osteosarcoma, port wine stain, rhabdomyosarcoma, Spitz nevus, and xanthogranuloma.
Differential diagnosis of pediatric tumors of the nasal cavity and paranasal sinuses: a 45-year multi-institutional review
DISCUSSION: Esthesioneuroblastoma (olfactory neuroblastoma) is a rare neuroectodermal tumour, (1) which is challenging for multidisciplinary management, as so far there is no known accepted standard therapy.
Rare presentation of olfactory neuroblastoma: case report
1 It may be mistaken for esthesioneuroblastoma because of its neuroectodermal histologic component and features of cribriform plate transgression.
Sinonasal teratocarcinosarcoma: MRI and F18-FDG-PET/CT imaging

Medical browser ?
Full browser ?