Corneal sensation measurements were obtained by performing Cochet-Bonnet esthesiometry
. CCM was performed on unilateral eyes of all subjects.
We did not perform esthesiometry
tests because of diurnal variability of corneal sensitivity , and approximately 45% of patients were contact lens users (as shown in Table 1), a condition reported to reduce corneal sensitivity .
was carried out as previous description using a Cochet-Bonnet esthesiometer (Luneau Ophtalmologie, Chartres Cedex, France)., The nylon monofilament had a maximal extended length of 60 mm with a diameter of 0.12 mm.
has been studied in different species, including humans (GOLEBIOWSY et al., 2011), cats (CHANG-LING, 1989; BLOCKER & VAN DER WOERT, 2001; WIESER et al., 2013), rabbits (WIESER et al., 2013), dogs (BARRETT et al., 1991; WIESER et al., 2013; KOBASHIGAWA et al., 2015), chinchillas (LIMA et al., 2010; MULLER et al., 2010), alpacas (WELIHOZKIY et al., 2011; RANKIN et al., 2012), goat, guinea pigs, cows and sheep (WIESER et al., 2013), birds (LACERDA et al., 2014), turtles (SOMMA et al., 2015) and horses (BROOKS et al., 2001; KAPS et al., 2003; WIESER et al., 2013).
Relation between corneal innervation with confocal microscopy and corneal sensitivity with noncontact esthesiometry
in patients with dry eye.
Physicians use devices for computer esthesiometry various updating for tool diagnostics of peripheral polyneuropathies in other countries.
During carrying out esthesiometry the investigated patients were in a prone position on a medical couch, blindly.
But computer esthesiometry had the highest significance both for higher or lower limbs.
In 71.4% of cases the "Computer esthesiometry" index 1 (normal vibration sensitivity) was corresponded to the "The Degree of diabetic polyneuropathy" index 1 (none DPN).
found that even 2 to 5 years after LASIK for high myopia, most patients experienced ocular surface discomfort consistent with dry eye syndrome despite the absence of clinical signs of ocular surface disease and with normal sensitivity when measured with noncontact esthesiometry
Subbasal nerve fiber regeneration after LASIK and LASEK assessed by noncontact esthesiometry
and in vivo confocal microscopy: prospective study.
Wassfi et al., "Relation between corneal innervation with confocal microscopy and corneal sensitivity with noncontact esthesiometry
in patients with dry eye," Investigative Ophthalmology & Visual Science, vol.