Esteratic site | definition of esteratic site by Medical dictionary
that part of a cholinesterase macromolecule that recognizes and binds acetylcholine. This combination results in the hydrolysis of the acetylcholine.
References in periodicals archive
The mechanism of inhibition of the enzyme is by reacting with the esteratic site
on the acetylcholinesterase molecule.
The anionic site attracts with quaternary nitrogen and esteratic site
attracts to carbonyl carbon (nucleophilic) of AChE inhibitor compounds (Colletier et al.
1) Organophosphorus compounds phosphorylates the esteratic site
of the enzyme cholinesterase (ACHE), due which, it is unable to hydrolyse acetylcholine.
Organophosphorus compounds combine with esteratic sites
of acetyl cholinesterase that is phosphorylated and phosphorylated esteratic sites