erythropoiesis-stimulating agent


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erythropoiesis-stimulating agent

Abbreviation: ESA.
Any drug that binds to cellular receptors for erythropoietin and encourages red blood cell production by the bone marrow. Members of this class of drugs, which include epoietin and darbopoietin, are used to treat anemia, e.g., in patients with chronic kidney disease, cancer, or aplastic anemia. ESAs are used as an alternative to red blood cell transfusions. Potential side effects of treatment include high blood pressure and an increased risk of blood clots.
See also: agent
References in periodicals archive ?
Current and upcoming erythropoiesis-stimulating agents, iron products, and other novel anemia medications.
Possible reasons for switching a patient between erythropoiesis-stimulating agents may include patient preference, injection site pain, hypersensitivity to one of the erythropoiesis-stimulating agents, stability/storage, dosing interval, lack of response to one of the erythropoiesis-stimulating agents and the support provided by the manufacturer.
Associations between changes in hemoglobin and administered erythropoiesis-stimulating agent and survival in hemodialysis patients.
Predictors of hyporesponsiveness to erythropoiesis-stimulating agents in hemodialysis patients.
Her hemoglobin (Hb) levels had been steadily declining despite escalating doses of an erythropoiesis-stimulating agent (ESA).

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